Literature DB >> 6743914

Prazosin inhibits small intestinal transit in the rat.

B D Rush, M J Ruwart.   

Abstract

Gastric emptying, small intestinal transit, and colonic transit were measured in fasted rats preimplanted with either duodenal or colonic cannulae. At the doses stated, prazosin (given subcutaneously) had no effect on gastric emptying or colonic transit, whereas small intestinal transit was significantly delayed.

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Year:  1984        PMID： 6743914      PMCID： PMC1987004          DOI： 10.1111/j.1476-5381.1984.tb10792.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


  4 in total

1.  Carbachol stimulation of gastrointestinal transit in the postoperative lleus rat.

Authors:  M J Ruwart; M S Klepper; B D Rush
Journal:  J Surg Res       Date:  1979-01       Impact factor: 2.192

2.  Evidence for noncholinergic mediation of small intestinal transit in the rat.

Authors:  M J Ruwart; M S Klepper; B D Rush
Journal:  J Pharmacol Exp Ther       Date:  1979-06       Impact factor: 4.030

3.  Postoperative ileus in the rat: physiopathology, etiology and treatment.

Authors:  A Dubois; V K Weise; I J Kopin
Journal:  Ann Surg       Date:  1973-12       Impact factor: 12.969

4.  Clonidine delays small intestinal transit in the rat.

Authors:  M J Ruwart; M S Klepper; B D Rush
Journal:  J Pharmacol Exp Ther       Date:  1980-03       Impact factor: 4.030
  4 in total
  1 in total

1.  Involvement of alpha-1 and alpha-2 adrenoceptors in the postlaparotomy intestinal motor disturbances in the rat.

Authors:  A Sagrada; M J Fargeas; L Bueno
Journal:  Gut       Date:  1987-08       Impact factor: 23.059
  1 in total

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