| Literature DB >> 6743469 |
R J McFarland, C R Corbett, P Taylor, A G Nash.
Abstract
The retained stone in the common bile duct remains a problem for the surgeon. Although more effective methods are available, mechanical flushing of the bile duct is, when successful, a simple solution. Pharmacological dilatation of the sphincter of Oddi is a logical adjunct to flushing. Pressure changes in the bile duct during flushing were studied in 20 postoperative patients with T-tube drains and the effectiveness of two drugs in reducing Omnopon induced spasm of the sphincter was compared. Hymecromone intravenously and lignocaine via the T-tube were equally effective, reducing sphincter activity in the majority of patients, but there was considerable individual variation.Entities:
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Year: 1984 PMID： 6743469 PMCID： PMC1463424 DOI： 10.1111/j.1365-2125.1984.tb02416.x
Source DB: PubMed Journal: Br J Clin Pharmacol ISSN： 0306-5251 Impact factor: 4.335