| Literature DB >> 6743314 |
C Furihata, Y Sato, M Hosaka, T Matsushima, F Furukawa, M Takahashi.
Abstract
Inductions of 200-fold increase in ornithine decarboxylase activity within 6 hours and 9-fold increase in DNA synthesis within 3 hours in rat stomach mucosa were observed after a single oral dose of saturated NaCl solution. NaCl caused dose-dependent induction of ornithine decarboxylase activity at doses of 0.25 to 1. 5g /kg body weight, and of DNA synthesis at doses of 0. 5g to 1. 5g /kg body weight. Administration of 1,3-diaminopropane one hour before NaCl inhibited the induction of ornithine decarboxylase activity in the stomach mucosa 3 and 6 hours after NaCl administration, but a single dose of 1,3-diaminopropane itself induced ornithine decarboxylase after 16 hours.Entities:
Mesh：
Substances：
Year: 1984 PMID： 6743314 DOI： 10.1016/0006-291x(84)90780-0
Source DB: PubMed Journal: Biochem Biophys Res Commun ISSN： 0006-291X Impact factor: 3.575