Literature DB >> 6740316

GM1 ganglioside treatment facilitates behavioral recovery from bilateral brain damage.

B A Sabel, M D Slavin, D G Stein.   

Abstract

Adult rats with bilateral lesions of the caudate nucleus were treated with GM1 ganglioside. Although animals injected with a control solution were severely impaired in their ability to learn a complex spatial task, those treated with ganglioside were able to learn spatial reversals.

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Year:  1984        PMID： 6740316     DOI： 10.1126/science.6740316

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  13 in total

Review 1.  Medical treatments of acute spinal cord injury.

Authors:  W Young
Journal:  J Neurol Neurosurg Psychiatry       Date:  1992-08       Impact factor: 10.154

Review 2.  Therapies targeting lipid peroxidation in traumatic brain injury.

Authors:  Tamil Selvan Anthonymuthu; Elizabeth Megan Kenny; Hülya Bayır
Journal:  Brain Res       Date:  2016-02-10       Impact factor: 3.252

3.  Enhanced sprouting of retinotectal fibers after early superior colliculus lesions in hamsters treated with gangliosides.

Authors:  B A Sabel; G E Schneider
Journal:  Exp Brain Res       Date:  1988       Impact factor: 1.972

Review 4.  Cognitive enhancement therapy for Alzheimer's disease. The way forward.

Authors:  L Parnetti; U Senin; P Mecocci
Journal:  Drugs       Date:  1997-05       Impact factor: 9.546

5.  Monosialoanglioside (GM1) prevents lead-induced neurotoxicity on long-term potentiation, SOD activity, MDA levels, and intracellular calcium levels of hippocampus in rats.

Authors:  Jia-Qi She; Ming Wang; Da-Miao Zhu; Mingliang Tang; Ju-Tao Chen; Lang Wang; Di-Yun Ruan
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2008-11-29       Impact factor: 3.000

6.  Open field behaviours and spatial learning performance in C57BL/6 mice: early stage effects of chronic GM1 ganglioside administration.

Authors:  S Fagioli; C Rossi-Arnaud; M Ammassari-Teule
Journal:  Psychopharmacology (Berl)       Date:  1991       Impact factor: 4.530

Review 7.  Spinal cord injury: a review of current therapy, future treatments, and basic science frontiers.

Authors:  Abhay K Varma; Arabinda Das; Gerald Wallace; John Barry; Alexey A Vertegel; Swapan K Ray; Naren L Banik
Journal:  Neurochem Res       Date:  2013-03-06       Impact factor: 3.996

Review 8.  Ganglioside function in the development and repair of the nervous system. From basic science to clinical application.

Authors:  S D Skaper; A Leon; G Toffano
Journal:  Mol Neurobiol       Date:  1989       Impact factor: 5.590

9.  Electrokinetic and electrostatic properties of bilayers containing gangliosides GM1, GD1a, or GT1. Comparison with a nonlinear theory.

Authors:  R V McDaniel; K Sharp; D Brooks; A C McLaughlin; A P Winiski; D Cafiso; S McLaughlin
Journal:  Biophys J       Date:  1986-03       Impact factor: 4.033

10.  GM1 gangliosides stimulate neuronal reorganization and reduce rotational asymmetry after hemitransections of the nigro-striatal pathway.

Authors:  B A Sabel; G L Dunbar; W M Butler; D G Stein
Journal:  Exp Brain Res       Date:  1985       Impact factor: 1.972
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