Literature DB >> 673846

The relationship between the activities of different pools of RNA polymerases I and II during PHA-stimulation of human lymphocytes.

C R Tillyer, P H Butterworth.   

Abstract

Following PHA-stimulation of lymphocytes in culture, it is known that nuclear RNA synthesis and the amount of extractable RNA polymerase activity rise in these cells. The relationship between these two phenomena has been examined. Using an in vitro assay system which discriminates between polymerase activity which is "engaged" in nuclear RNA synthesis and a pool of "free" enzyme, the data suggest that the factors regulating the interaction between these two pools of enzyme activity are different for forms I and II RNA polymerases.

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Year:  1978        PMID: 673846      PMCID: PMC342147          DOI: 10.1093/nar/5.6.2099

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN: 0305-1048            Impact factor:   16.971


  27 in total

1.  POSSIBLE SYNTHESIS OF POLYRIBONUCLEOTIDES OF KNOWN BASE-TRIPLET SEQUENCES.

Authors:  R W MASTER
Journal:  Nature       Date:  1965-04-03       Impact factor: 49.962

2.  Phytohaemagglutinin stimulation of human lymphocytes during amino-acid deprivation. RNA polymerase I activity of isolated nuclei.

Authors:  C Dauphinais; W I Waithe
Journal:  Eur J Biochem       Date:  1977-08-15

3.  Mechanism of aflatoxin B1 inhibition of rat hepatic nuclear RNA synthesis.

Authors:  F L Yu
Journal:  J Biol Chem       Date:  1977-05-25       Impact factor: 5.157

4.  Growth and maturation of single clones of normal murine T and B lymphocytes in vitro.

Authors:  J Andersson; A Coutinho; F Melchers; T Watanabe
Journal:  Cold Spring Harb Symp Quant Biol       Date:  1977

5.  Control mechanism of ribonucleic acid synthesis in eukaryotes. The effect of amino acid and glucose starvation and cycloheximide on yeast deoxyribonucleic acid-dependent ribonucleic acid polymerases.

Authors:  K J Gross; A O Pogo
Journal:  J Biol Chem       Date:  1974-01-25       Impact factor: 5.157

6.  Multiple forms of deoxyribonucleic acid-dependent ribonucleic acid polymerase in Xenopus laevis. Levels of activity during oocyte and embryonic development.

Authors:  R G Roeder
Journal:  J Biol Chem       Date:  1974-01-10       Impact factor: 5.157

7.  Initiation of RNA synthesis in isolated nuclei.

Authors:  E Gilboa; H Soreq; H Aviv
Journal:  Eur J Biochem       Date:  1977-07-15

8.  Subpopulations of human T cells identified by receptors for immunoglobulins and mitogen responsiveness.

Authors:  L Moretta; M Ferrarini; M C Mingari; A Moretta; S R Webb
Journal:  J Immunol       Date:  1976-12       Impact factor: 5.422

9.  Forms AI and AII DNA-dependent RNA polymerases as components of two defined pools of polymerase activity in mammalian cells.

Authors:  B L Kellas; J L Austoker; T J Beebee; P H Butterworth
Journal:  Eur J Biochem       Date:  1977-02

10.  Functional analysis of two human T-cell subpopulations: help and suppression of B-cell responses by T cells bearing receptors for IgM or IgG.

Authors:  L Moretta; S R Webb; C E Grossi; P M Lydyard; M D Cooper
Journal:  J Exp Med       Date:  1977-07-01       Impact factor: 14.307

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  3 in total

1.  Isolation, fractionation and reconstitution of a nuclear extract capable of transcribing ribosomal DNA.

Authors:  R E Haglund; L I Rothblum
Journal:  Mol Cell Biochem       Date:  1987-01       Impact factor: 3.396

Review 2.  Cellular and molecular aspects of immune system aging.

Authors:  D L Doggett; M P Chang; T Makinodan; B L Strehler
Journal:  Mol Cell Biochem       Date:  1981-07       Impact factor: 3.396

3.  Transcriptionally active RNA polymerases from Morris hepatomas and rat liver. Elucidation of the mechanism for the preferential increase in the tumour RNA polymerase I.

Authors:  B W Duceman; S T Jacob
Journal:  Biochem J       Date:  1980-09-15       Impact factor: 3.857

  3 in total

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