Literature DB >> 6738080

Tracheal phenol red secretion, a new method for screening mucosecretolytic compounds.

H Engler, I Szelenyi.   

Abstract

A simple method for screening drugs that influence tracheobronchial secretion has been described. After i.p. application of a phenol red solution, part of the dye is secreted into the tracheal lumen. This basal secretion is increased by both parasympathomimetics and sympathomimetics. In addition, expectorants are also capable of increasing tracheal phenol red output. Therefore this method is suitable for the study of drugs that may be capable of influencing tracheobronchial secretion.

Entities:  

Mesh:

Substances:

Year:  1984        PMID: 6738080     DOI: 10.1016/0160-5402(84)90033-0

Source DB:  PubMed          Journal:  J Pharmacol Methods        ISSN: 0160-5402


  11 in total

Review 1.  [Pharmacology of Sinupret. Recent results on the rational for the Sinupret compound].

Authors:  C Ismail
Journal:  HNO       Date:  2005-05       Impact factor: 1.284

2.  Mucolytic activity of azelastine in mice and rats.

Authors:  N Chand; J E Harrison; S Rooney; W Diamantis; R D Sofia
Journal:  Agents Actions       Date:  1993-03

3.  Influence of azelastine and some selected drugs on mucociliary clearance.

Authors:  U Achterrath-Tuckermann; V Saano; E Minker; F Stroman; I Arny; S Joki; J Nuutinen; I Szelenyi
Journal:  Lung       Date:  1992       Impact factor: 2.584

4.  Expectorant and antitussive effect of Hedera helix and Rhizoma coptidis extracts mixture.

Authors:  Kee Jae Song; Young-June Shin; Kang Ro Lee; Eun Jung Lee; Yun Suk Suh; Kyung-Su Kim
Journal:  Yonsei Med J       Date:  2015-05       Impact factor: 2.759

5.  Antitussive, expectorant and analgesic effects of the ethanol seed extract of Picralima nitida (Stapf) Th. & H. Durand.

Authors:  Gabriel Dapaah; George Asumeng Koffuor; Priscilla Kolibea Mante; Inemesit Okon Ben
Journal:  Res Pharm Sci       Date:  2016 Mar-Apr

6.  The possible mode of antitussive and expectorant activity of the ethanol seed extracts of Picralima nitida ((Stapf) Th. & H. Durand).

Authors:  Gabriel Dapaah; George Asumeng Koffuor; Priscilla Kolibea Mante; Inemesit Okon Ben
Journal:  J Tradit Complement Med       Date:  2016-07-13

7.  Suhuang Antitussive Capsules-Ameliorative Effects on LPS-Induced Sputum Obstruction in Mice Through Promoting HGF Secretion.

Authors:  Xiyang Tong; Rongyao Liang; Yuning Jia; Weiwei Qin; Chao Guo; Xingdong Wu; Zhen Wang; Dong Chen; Ninghua Tan
Journal:  Front Pharmacol       Date:  2019-12-19       Impact factor: 5.810

8.  Anti-inflammatory, expectorant, and antitussive properties of Kyeongok-go in ICR mice.

Authors:  Jin-Ryul Hu; Chul-Jong Jung; Seong-Min Ku; Dae-Hwa Jung; Khawaja Muhammad Imran Bashir; Sae-Kwang Ku; Jae-Suk Choi
Journal:  Pharm Biol       Date:  2021-12       Impact factor: 3.503

9.  Spiralosides A-C, Three New C27-Steroidal Glycoalkaloids from the Fruits of Solanum spirale.

Authors:  Dan Li; Yun-Li Zhao; Xu-Jie Qin; Lu Liu; Xing-Wei Yang; Ying-Ying Chen; Bei Wang; Xin Wei; Ya-Ping Liu; Xiao-Dong Luo
Journal:  Nat Prod Bioprospect       Date:  2016-06-18

10.  In Vivo Evaluation of the Antiasthmatic, Antitussive, and Expectorant Activities and Chemical Components of Three Elaeagnus Leaves.

Authors:  Yuebin Ge; Fei Zhang; Qin Qin; Yingying Shang; Dingrong Wan
Journal:  Evid Based Complement Alternat Med       Date:  2015-10-21       Impact factor: 2.629

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.