| Literature DB >> 6737372 |
E McDonald, M P Jarrett, G Schiffman, A I Grayzel.
Abstract
Antibody levels to 12 different pneumococcal capsular polysaccharides as well as the combined mean antibody level were measured in 19 patients with systemic lupus erythematosus (SLE) at 1, 2 and 3 years after immunization with a polyvalent pneumococcal vaccine and compared to 5 normal control subjects immunized at the same time. The mean levels in the 19 SLE patients were lower in all 3 years but the difference reached significance only in Year 1. At 3 years, 8 of the 19 SLE patients had levels below that considered to be protective and one such patient developed a pneumococcal pneumonia.Entities:
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Year: 1984 PMID: 6737372
Source DB: PubMed Journal: J Rheumatol ISSN: 0315-162X Impact factor: 4.666