| Literature DB >> 6736277 |
W F Kuhn, D R Jones, S B Lippmann, C K Embry, W M Williams, M S Manshadi, H E Hurst.
Abstract
Elimination of amitriptyline and/or metabolite after overdoses may be delayed because of impaired metabolism. A case is described where this was possibly related to hepatotoxicity. Metabolite concentrations, including 10-OH-derivatives, were highly elevated. The biological properties and clinical significance of these metabolites merit further study.Entities:
Mesh：
Substances：
Year: 1984 PMID： 6736277
Source DB: PubMed Journal: J Clin Psychopharmacol ISSN： 0271-0749 Impact factor: 3.153