Literature DB >> 6736013

2-Propylthiouracil does not replace glutathione for the glutathione transferases.

W H Habig, W B Jakoby, C Guthenberg, B Mannervik, D L Vander Jagt.   

Abstract

2-Propylthiouracil has been reported as replacing glutathione as a substrate for the glutathione transferases of rat liver. This observation has been examined with several homogeneous glutathione transferases that were prepared from human and rat liver by different methods in three laboratories. No evidence was obtained for 2-propylthiouracil as a substrate for glutathione transferase in the several reactions tested.

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Year:  1984        PMID: 6736013

Source DB:  PubMed          Journal:  J Biol Chem        ISSN: 0021-9258            Impact factor:   5.157


  7 in total

1.  Inhibition and recognition studies on the glutathione-binding site of equine liver glutathione S-transferase.

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Journal:  Biochem J       Date:  1990-10-01       Impact factor: 3.857

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Journal:  Plant Foods Hum Nutr       Date:  2009-12       Impact factor: 3.921

3.  Stimulation of mouse liver glutathione S-transferase activity in propylthiouracil-treated mice in vivo by tri-iodothyronine.

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Journal:  Biochem J       Date:  1986-01-15       Impact factor: 3.857

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5.  Antioxidant effects of Dendropanax morbifera Léveille extract in the hippocampus of mercury-exposed rats.

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6.  Dendropanax morbifera Léveille extract facilitates cadmium excretion and prevents oxidative damage in the hippocampus by increasing antioxidant levels in cadmium-exposed rats.

Authors:  Woosuk Kim; Dae Won Kim; Dae Young Yoo; Hyo Young Jung; Sung Min Nam; Jong Whi Kim; Soon-Min Hong; Dong-Woo Kim; Jung Hoon Choi; Seung Myung Moon; Yeo Sung Yoon; In Koo Hwang
Journal:  BMC Complement Altern Med       Date:  2014-10-31       Impact factor: 3.659

7.  Diallyl Disulfide Prevents Cyclophosphamide-Induced Hemorrhagic Cystitis in Rats through the Inhibition of Oxidative Damage, MAPKs, and NF-κB Pathways.

Authors:  Sung Hwan Kim; In Chul Lee; Je Won Ko; Changjong Moon; Sung Ho Kim; In Sik Shin; Young Won Seo; Hyoung Chin Kim; Jong Choon Kim
Journal:  Biomol Ther (Seoul)       Date:  2015-03-01       Impact factor: 4.634

  7 in total

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