| Literature DB >> 6733694 |
P Liu, P J Cheng, T S Ing, J T Daugirdas, R Jeevanandhan, L S Soung, S Galinis.
Abstract
In vitro binding of amantadine to plasma protein was assessed by ultrafiltration of plasma samples (from a blood bank) to which amantadine hydrochloride had been added. Approximately two-thirds of the amantadine was found to be protein-bound. The degree of protein binding was constant over a plasma amantadine concentration range of 100-2,000 ng/ml.Entities:
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Year: 1984 PMID： 6733694 DOI： 10.1097/00002826-198406000-00005
Source DB: PubMed Journal: Clin Neuropharmacol ISSN： 0362-5664 Impact factor: 1.592