Literature DB >> 6732767

Inositol uptake by cultured isolated rat Schwann cells.

S Segal, S M Hwang, J Stern, D Pleasure.   

Abstract

The uptake of radiolabeled myo-inositol by Schwann cells isolated from the sciatic nerve of 2-4 day old rats was found to occur by a saturable, sodium-dependent phlorizin-inhibited mechanism with an estimated Km of 30 microM. The system was inhibited by galactose and glucose but not by galactitol. At high concentrations of myo-inositol, a diffusion-like process appeared to be functional. The characteristics of the saturable system are very similar to those of myo-inositol uptake by the endoneural fascicle preparation of sciatic nerve.

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Year:  1984        PMID： 6732767     DOI： 10.1016/0006-291x(84)91280-4

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  7 in total

1.  Down's syndrome fibroblasts exhibit enhanced inositol uptake.

Authors:  B R Fruen; B R Lester
Journal:  Biochem J       Date:  1990-08-15       Impact factor: 3.857

2.  Mitogen-activated protein kinase and its activator are regulated by hypertonic stress in Madin-Darby canine kidney cells.

Authors:  T Itoh; A Yamauchi; A Miyai; K Yokoyama; T Kamada; N Ueda; Y Fujiwara
Journal:  J Clin Invest       Date:  1994-06       Impact factor: 14.808

3.  The characteristics, capacity and receptor regulation of inositol uptake in 1321N1 astrocytoma cells.

Authors:  I H Batty; A Michie; M Fennel; C P Downes
Journal:  Biochem J       Date:  1993-08-15       Impact factor: 3.857

4.  Feedback inhibition of aldose reductase gene expression in rat renal medulla. Galactitol accumulation reduces enzyme mRNA levels and depletes cellular inositol content.

Authors:  C Bondy; B D Cowley; S L Lightman; P F Kador
Journal:  J Clin Invest       Date:  1990-10       Impact factor: 14.808

5.  Uptake and metabolism of myo-inositol by L1210 leukaemia cells.

Authors:  J D Moyer; N Malinowski; E A Napier; J Strong
Journal:  Biochem J       Date:  1988-08-15       Impact factor: 3.857

6.  Hyperglycemia triggers abnormal signaling and proliferative responses in Schwann cells.

Authors:  Khaldoun Almhanna; Pamela L Wilkins; James R Bavis; Subash Harwalkar; Liliana N Berti-Mattera
Journal:  Neurochem Res       Date:  2002-11       Impact factor: 3.996

7.  myo-inositol transport and metabolism in fetal-bovine aortic endothelial cells.

Authors:  G T Berry; R A Johanson; J E Prantner; B States; J R Yandrasitz
Journal:  Biochem J       Date:  1993-11-01       Impact factor: 3.857
  7 in total

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