Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Messenger RNAs coding for mouse major urinary proteins are differentially induced by testosterone.

Literature DB >> 6732752

Messenger RNAs coding for mouse major urinary proteins are differentially induced by testosterone.

Abstract

We have investigated the sexual dimorphism of the mouse major urinary proteins (MUPs) by isoelectric focusing (IEF). In each of two inbred strains which have different male patterns (C57BL and BALB/c), the females show a simpler pattern with fewer prominent components. The main female component is different in each strain, and these may be the products of allelic structural genes. Treatment with testosterone induces the excretion of MUPs with the male pattern. The in vitro translation of hybrid-selected MUP mRNA was studied in the same way. Again, the female patterns were simpler than the male, and the patterns obtained with female mRNA from the two inbred strains were different. When the females were treated with testosterone, a male or male-like pattern was obtained. We argue that some MUP structural genes are quite actively transcribed in females and that the transcription of others is dependent to different degrees upon induction by testosterone.

Entities: Chemical Gene Species

Mesh：

Substances：

Year: 1984 PMID： 6732752 DOI： 10.1007/BF00484236

Source DB: PubMed Journal: Biochem Genet ISSN： 0006-2928 Impact factor: 1.890

17 in total

1. ELECTROPHORETIC VARIATION AND SEX DIMORPHISM OF THE MAJOR URINARY PROTEIN COMPLEX IN INBRED MICE: A NEW GENETIC MARKER.

Authors: J S FINLAYSON; M POTTER; C R RUNNER
Journal: J Natl Cancer Inst Date: 1963-07 Impact factor: 13.506

2. Multiple genes coding for the androgen-regulated major urinary proteins of the mouse.

Authors: N D Hastie; W A Held; J J Toole
Journal: Cell Date: 1979-06 Impact factor: 41.582

3. Mapping the structural genes coding for the major urinary proteins in the mouse: combined use of recombinant inbred strains and somatic cell hybrids.

Authors: K L Bennett; P A Lalley; R K Barth; N D Hastie
Journal: Proc Natl Acad Sci U S A Date: 1982-02 Impact factor: 11.205

4. The gene family for major urinary proteins: expression in several secretory tissues of the mouse.

Authors: P H Shaw; W A Held; N D Hastie
Journal: Cell Date: 1983-03 Impact factor: 41.582

5. Allelic variation at several different genetic loci determines the major urinary protein phenotype of inbred mouse strains.

Authors: S Hainey; J O Bishop
Journal: Genet Res Date: 1982-02 Impact factor: 1.588

6. Molecular cloning of cDNA sequences transcribed from mouse liver endoplasmic reticulum poly(A)mRNA.

Authors: P M Clissold; J O Bishop
Journal: Gene Date: 1981-11 Impact factor: 3.688

7. Variation in mouse major urinary protein (MUP) genes and the MUP gene products within and between inbred lines.

Authors: P M Clissold; J O Bishop
Journal: Gene Date: 1982-06 Impact factor: 3.688

8. Isolation of a cDNA clone for mouse urinary proteins: age- and sex-related expression of mouse urinary protein genes is transcriptionally controlled.

Authors: E Derman
Journal: Proc Natl Acad Sci U S A Date: 1981-09 Impact factor: 11.205

10. A Mup promoter-thymidine kinase reporter gene shows relaxed tissue-specific expression and confers male sterility upon transgenic mice.

Authors: R Al-Shawi; J Burke; C T Jones; J P Simons; J O Bishop
Journal: Mol Cell Biol Date: 1988-11 Impact factor: 4.272

Messenger RNAs coding for mouse major urinary proteins are differentially induced by testosterone.

1. ELECTROPHORETIC VARIATION AND SEX DIMORPHISM OF THE MAJOR URINARY PROTEIN COMPLEX IN INBRED MICE: A NEW GENETIC MARKER.

2. Multiple genes coding for the androgen-regulated major urinary proteins of the mouse.

3. Mapping the structural genes coding for the major urinary proteins in the mouse: combined use of recombinant inbred strains and somatic cell hybrids.

4. The gene family for major urinary proteins: expression in several secretory tissues of the mouse.

5. Allelic variation at several different genetic loci determines the major urinary protein phenotype of inbred mouse strains.

6. Molecular cloning of cDNA sequences transcribed from mouse liver endoplasmic reticulum poly(A)mRNA.

7. Variation in mouse major urinary protein (MUP) genes and the MUP gene products within and between inbred lines.

8. Isolation of a cDNA clone for mouse urinary proteins: age- and sex-related expression of mouse urinary protein genes is transcriptionally controlled.

9. Structure of mouse major urinary protein genes: different splicing configurations in the 3'-non-coding region.

10. Structural genes of the mouse major urinary protein are on chromosome 4.

1. Modulation of exploratory behavior in female mice by protein-borne male urinary molecules.

Review 2. Oxidative stress and condition-dependent sexual signals: more than just seeing red.

3. Studies of an Androgen-Binding Protein Knockout Corroborate a Role for Salivary ABP in Mouse Communication.

4. Intraspecific evolution of a gene family coding for urinary proteins.

5. Maternal transfer of BDE-47 to offspring and neurobehavioral development in C57BL/6J mice.

6. The 45-kb unit of major urinary protein gene organization is a gigantic imperfect palindrome.

7. Experience-Dependent Plasticity Drives Individual Differences in Pheromone-Sensing Neurons.

8. Acceleration of puberty onset in female mice by male urinary proteins.

9. Molecular heterogeneity in the Major Urinary Proteins of the house mouse Mus musculus.

10. A Mup promoter-thymidine kinase reporter gene shows relaxed tissue-specific expression and confers male sterility upon transgenic mice.