Literature DB >> 6732705

The hippocampus, context, and information processing.

G Winocur, M Gilbert.   

Abstract

Two experiments are described in which groups of rats with bilateral hippocampal lesions, cortical lesions, and operated controls are compared on tests of discrimination learning, retention, and reversal learning. Experiment 1 examined the effects of varying prior training and context on new learning. Experiment 2 used a transfer paradigm to compare extent of original learning by hippocampal and control groups in a discrimination task involving multiple discriminanada . The major findings were that rats with hippocampal damage were less efficient at processing information and were more constrained by contextual influences than control rats.

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Year:  1984        PMID: 6732705     DOI: 10.1016/s0163-1047(84)90146-8

Source DB:  PubMed          Journal:  Behav Neural Biol        ISSN: 0163-1047


  4 in total

Review 1.  Multiple roles for orexin/hypocretin in addiction.

Authors:  Stephen V Mahler; Rachel J Smith; David E Moorman; Gregory C Sartor; Gary Aston-Jones
Journal:  Prog Brain Res       Date:  2012       Impact factor: 2.453

2.  Chronic unpredictable intermittent restraint stress disrupts spatial memory in male, but not female rats.

Authors:  Dylan N Peay; Hovhannes M Saribekyan; Priscilla A Parada; Elizabeth M Hanson; Bryce S Badaruddin; Jessica M Judd; Megan E Donnay; Diego Padilla-Garcia; Cheryl D Conrad
Journal:  Behav Brain Res       Date:  2020-01-30       Impact factor: 3.332

3.  Delayed noradrenergic activation in the dorsal hippocampus promotes the long-term persistence of extinguished fear.

Authors:  Ning Chai; Jian-Feng Liu; Yan-Xue Xue; Chang Yang; Wei Yan; Hui-Min Wang; Yi-Xiao Luo; Hai-Shui Shi; Ji-Shi Wang; Yan-Ping Bao; Shi-Qiu Meng; Zeng-Bo Ding; Xue-Yi Wang; Lin Lu
Journal:  Neuropsychopharmacology       Date:  2014-02-19       Impact factor: 7.853

Review 4.  Norepinephrine, beyond the Synapse: Coordinating Epigenetic Codes for Memory.

Authors:  Sabyasachi Maity; Raman Abbaspour; David Nahabedian; Steven A Connor
Journal:  Int J Mol Sci       Date:  2022-08-31       Impact factor: 6.208

  4 in total

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