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Literature DB >> 6732604

Nasal responsiveness to methacholine stimulation in allergic rhinitis patients.

K Asakura, K Enomoto, H Ara, E Azuma, A Kataura.

Abstract

We examined the nasal responsiveness to topical methacholine application in allergic rhinitis and non-allergic chronic rhinitis patients, and in control subjects. Methacholine responsiveness was significantly higher in allergic rhinitis patients than in non-allergic patients and control subjects. In perennial rhinitis, methacholine responsiveness correlated with the severity of daily nasal symptoms and those provoked by specific allergen challenge tests. Among nasal symptoms, hyper-rhinorrhoea was found to be closely related to methacholine responsiveness. As a result of these findings, the possibility of cholinergic hyper-reactivity in allergic rhinitis patients is discussed.

Entities: Chemical Disease Species

Mesh：

Substances：
Methacholine Compounds

Year: 1984 PMID： 6732604 DOI： 10.1007/BF00464255

Source DB: PubMed Journal: Arch Otorhinolaryngol ISSN： 0302-9530

14 in total

1. The effect of beta adrenergic blockade on bronchial sensitivity to acetyl-beta-methacholine in normal and allergic rhinitis subjects.

Authors: R G Townley; S McGeady; A Bewtra
Journal: J Allergy Clin Immunol Date: 1976-04 Impact factor: 10.793

2. COMPARATIVE ACTION OF ACETYL-BETA-METHYL CHOLINE AND HISTAMINE ON THE RESPIRATORY TRACT IN NORMALS, PATIENTS WITH HAY FEVER, AND SUBJECTS WITH BRONCHIAL ASTHMA.

Authors: J J Curry
Journal: J Clin Invest Date: 1947-05 Impact factor: 14.808

3. Immunological release of histamine and slow reacting substance of anaphylaxis from human lung. II. Influence of cellular levels of cyclic AMP.

Authors: R P Orange; M A Kaliner; P J Laraia; K F Austen
Journal: Fed Proc Date: 1971 Nov-Dec

Review 4. Mediators of nasal allergy.

Authors: N Mygind
Journal: J Allergy Clin Immunol Date: 1982-09 Impact factor: 10.793

5. Vidian neurectomy for allergic rhinitis. Evaluation of long-term results and some problems concerning operative therapy.

Authors: A Konno; K Togawa
Journal: Arch Otorhinolaryngol Date: 1979

6. Metabolism of cyclic nucleotides in allergic rhinitis: studies on lymphocytes, granulocytes, and plasma level.

Authors: K Asakura; A Kataura
Journal: Arch Otorhinolaryngol Date: 1979

7. Airway responses to methacholine in allergic and nonallergic subjects.

Authors: J E Fish; R R Rosenthal; G Batra; H Menkes; W Summer; S Permutt; P Norman
Journal: Am Rev Respir Dis Date: 1976-05

8. Bronchial sensitivity to methacholine in current and former asthmatic and allergic rhinitis patients and control subjects.

Authors: R G Townley; U Y Ryo; B M Kolotkin; B Kang
Journal: J Allergy Clin Immunol Date: 1975-12 Impact factor: 10.793

Nasal responsiveness to methacholine stimulation in allergic rhinitis patients.

1. The effect of beta adrenergic blockade on bronchial sensitivity to acetyl-beta-methacholine in normal and allergic rhinitis subjects.

2. COMPARATIVE ACTION OF ACETYL-BETA-METHYL CHOLINE AND HISTAMINE ON THE RESPIRATORY TRACT IN NORMALS, PATIENTS WITH HAY FEVER, AND SUBJECTS WITH BRONCHIAL ASTHMA.

3. Immunological release of histamine and slow reacting substance of anaphylaxis from human lung. II. Influence of cellular levels of cyclic AMP.

Review 4. Mediators of nasal allergy.

5. Vidian neurectomy for allergic rhinitis. Evaluation of long-term results and some problems concerning operative therapy.

6. Metabolism of cyclic nucleotides in allergic rhinitis: studies on lymphocytes, granulocytes, and plasma level.

7. Airway responses to methacholine in allergic and nonallergic subjects.

8. Bronchial sensitivity to methacholine in current and former asthmatic and allergic rhinitis patients and control subjects.

9. Cholinergic nervous system and immediate hypersensitivity. II. An analysis of pupillary responses.

10. Role of the vidian nerve in nasal allergy.

1. Cyclic nucleotide levels of nasal secretions in allergic patients and control subjects.

2. Rhinovirus 39 infection in allergic and nonallergic subjects.