| Literature DB >> 6732407 |
B J Brooks, H E Broxmeyer, C F Bryan, S H Leech.
Abstract
Hematologic complications of systemic lupus erythematosus (SLE) usually involve peripheral destruction of blood elements. We report a case of SLE-associated aplastic anemia in which an IgG complement-dependent antibody, obtained from the patient's disease-phase serum but not remission-phase serum, suppressed growth of granulocyte-macrophage progenitor cells from bone marrow of normal donors in vitro. Therapy with plasmapheresis and immunosuppression resulted in lasting remission.Entities:
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Year: 1984 PMID: 6732407
Source DB: PubMed Journal: Arch Intern Med ISSN: 0003-9926