Literature DB >> 6732239

myo-Inositol-1-phosphate synthase from pine pollen: sulfhydryl involvement at the active site.

S C Gumber, M W Loewus, F A Loewus.   

Abstract

myo-Inositol-1-phosphate synthase [EC 5.5.1.4; 1L-myo-inositol-1-phosphate lyase, (isomerizing)] from Pinus ponderosa pollen has been partially purified and characterized. It has a pH optimum between 7.25 and 7.75. The km for D-glucose 6-phosphate (NAD+ constant at 1 mM) is 0.33 mM. Inhibition by p-chloromercuribenzoate and N-ethylmaleimide, and partial protection against this inhibition by D-glucose 6-phosphate in the presence of NAD+, suggests that there is sulfhydryl group involvement at the substrate binding site.

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Year:  1984        PMID： 6732239     DOI： 10.1016/0003-9861(84)90400-4

Source DB:  PubMed          Journal:  Arch Biochem Biophys        ISSN： 0003-9861            Impact factor:   4.013


  5 in total

1.  The Arabidopsis thaliana Myo-inositol 1-phosphate synthase1 gene is required for Myo-inositol synthesis and suppression of cell death.

Authors:  Janet L Donahue; Shannon R Alford; Javad Torabinejad; Rachel E Kerwin; Aida Nourbakhsh; W Keith Ray; Marcy Hernick; Xinyi Huang; Blair M Lyons; Pyae P Hein; Glenda E Gillaspy
Journal:  Plant Cell       Date:  2010-03-09       Impact factor: 11.277

2.  L-myo-lnositol 1-Phosphate Synthase from Plant Sources (Characteristics of the Chloroplastic and Cytosolic Enzymes).

Authors:  A. RayChaudhuri; N. C. Hait; S. Dasgupta; T. J. Bhaduri; R. Deb; A. L. Majumder
Journal:  Plant Physiol       Date:  1997-10       Impact factor: 8.340

3.  Biosynthesis of Di-myo-inositol-1,1'-phosphate, a novel osmolyte in hyperthermophilic archaea.

Authors:  L Chen; E T Spiliotis; M F Roberts
Journal:  J Bacteriol       Date:  1998-08       Impact factor: 3.490

Review 4.  Mobile forms of carbon in trees: metabolism and transport.

Authors:  Pia Guadalupe Dominguez; Totte Niittylä
Journal:  Tree Physiol       Date:  2022-03-09       Impact factor: 4.196

5.  Myo-inositol-1-phosphate synthase (Ino-1) functions as a protection mechanism in Corynebacterium glutamicum under oxidative stress.

Authors:  Can Chen; Keqi Chen; Tao Su; Bing Zhang; Guizhi Li; Junfeng Pan; Meiru Si
Journal:  Microbiologyopen       Date:  2018-10-01       Impact factor: 3.139
  5 in total

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