Literature DB >> 6731472

Glutathione and its redox system in diabetic polymorphonuclear leukocytes.

S N Chari, N Nath, A B Rathi.   

Abstract

The level of reduced glutathione in diabetic polymorphonuclear leukocytes was found to be significantly decreased compared to normal. Although the activity of glutathione reductase remained unchanged, the activity of glutathione peroxidase was found to be decreased in the diabetic state. Ketosis was not found to additionally aggravate the glutathione system. Polymorphonuclear leukocytes obtained from insulin-treated patients showed significant restoration.

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Year:  1984        PMID： 6731472     DOI： 10.1097/00000441-198405000-00004

Source DB:  PubMed          Journal:  Am J Med Sci        ISSN： 0002-9629            Impact factor:   2.378


  7 in total

Review 1.  Oxidative stress and insulin action: is there a relationship?

Authors:  G Paolisso; D Giugliano
Journal:  Diabetologia       Date:  1996-03       Impact factor: 10.122

2.  Dietary fish oil augments nitric oxide production or release in patients with type 2 (non-insulin-dependent) diabetes mellitus.

Authors:  G E McVeigh; G M Brennan; G D Johnston; B J McDermott; L T McGrath; W R Henry; J W Andrews; J R Hayes
Journal:  Diabetologia       Date:  1993-01       Impact factor: 10.122

3.  Induction of nitric oxide synthesis in J774 cells lowers intracellular glutathione: effect of modulated glutathione redox status on nitric oxide synthase induction.

Authors:  J S Hothersall; F Q Cunha; G H Neild; A A Norohna-Dutra
Journal:  Biochem J       Date:  1997-03-01       Impact factor: 3.857

4.  Effect of inhibition of glutathione synthesis on insulin action: in vivo and in vitro studies using buthionine sulfoximine.

Authors:  M Khamaisi; O Kavel; M Rosenstock; M Porat; M Yuli; N Kaiser; A Rudich
Journal:  Biochem J       Date:  2000-07-15       Impact factor: 3.857

Review 5.  The role of endothelium in the pathogenesis of diabetic microangiopathy.

Authors:  M La Selva; E Beltramo; P Passera; M Porta; G M Molinatti
Journal:  Acta Diabetol       Date:  1993       Impact factor: 4.280

6.  Fermented milk, Kefram-Kefir enhances glucose uptake into insulin-responsive muscle cells.

Authors:  Kiichiro Teruya; Maiko Yamashita; Rumi Tominaga; Tsutomu Nagira; Sun-Yup Shim; Yoshinori Katakura; Sennosuke Tokumaru; Koichiro Tokumaru; David Barnes; Sanetaka Shirahata
Journal:  Cytotechnology       Date:  2002-11       Impact factor: 2.058

7.  Intimal redox stress: accelerated atherosclerosis in metabolic syndrome and type 2 diabetes mellitus. Atheroscleropathy.

Authors:  Melvin R Hayden; Suresh C Tyagi
Journal:  Cardiovasc Diabetol       Date:  2002-09-27       Impact factor: 9.951
  7 in total

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