| Literature DB >> 6731181 |
C Maśliński, D Kierska, K Sasiak, B Adamas.
Abstract
The hypothesis that failure of histamine (Hi)-mediated inter and intracellular cell-cell communication may be involved in the control of cellular growth has been tested in leukaemia-bearing mice and fibrosarcoma-bearing rats. In all examined tissues of mice bearing leukaemia L1210 cells and rats bearing methylcholanthrene fibrosarcoma histamine content was higher than in controls. Tissues of fibrosarcoma-bearing rats more intensively metabolized 14C-Hi and oxidative pathway was predominant. Histamine metabolic activity as well as histamine catabolic pathways do not differ in leukaemic mice as compared with the controls.Entities:
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Year: 1984 PMID: 6731181 DOI: 10.1007/BF01973858
Source DB: PubMed Journal: Agents Actions ISSN: 0065-4299