Literature DB >> 6729843

Purification of thirteen toxins active on mice from the venom of the North African scorpion Buthus occitanus tunetanus.

M F Martin, H Rochat.   

Abstract

A combination of several equilibrium chromatographic steps permitted us to purify thirteen proteins from the venom of Buthus occitanus tunetanus using the mouse as the test animal for lethality measurement. These proteins have been characterized by their amino acid composition and, for seven of them, by their N-terminal or complete amino acid sequence. The structural data obtained correlate well with the pharmacological and antigenic properties of the neurotoxins.

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Year:  1984        PMID： 6729843     DOI： 10.1016/0041-0101(84)90028-x

Source DB:  PubMed          Journal:  Toxicon        ISSN： 0041-0101            Impact factor:   3.033


  7 in total

1.  Involvement of Cholinergic and Adrenergic Receptors in Pathogenesis and Inflammatory Response Induced by Alpha-Neurotoxin Bot III of Scorpion Venom.

Authors:  Imene Nakib; Marie-France Martin-Eauclaire; Fatima Laraba-Djebari
Journal:  Inflammation       Date:  2016-10       Impact factor: 4.092

2.  A first exploration of the venom of the Buthus occitanus scorpion found in southern France.

Authors:  Marie-France Martin-Eauclaire; Frank Bosmans; Brigitte Céard; Sylvie Diochot; Pierre E Bougis
Journal:  Toxicon       Date:  2014-01-10       Impact factor: 3.033

3.  [Venomous animals and their venoms].

Authors:  G G Habermehl; H C Krebs
Journal:  Naturwissenschaften       Date:  1986-08

4.  In vitro leishmanicidal activity of Tityus discrepans scorpion venom.

Authors:  Adolfo Borges; Sylvia Silva; Huub J M Op den Camp; Elena Velasco; Marco Alvarez; Marcelo J M Alfonzo; Alicia Jorquera; Leonardo De Sousa; Olinda Delgado
Journal:  Parasitol Res       Date:  2006-03-15       Impact factor: 2.289

5.  Modular organization of α-toxins from scorpion venom mirrors domain structure of their targets, sodium channels.

Authors:  Anton O Chugunov; Anna D Koromyslova; Antonina A Berkut; Steve Peigneur; Jan Tytgat; Anton A Polyansky; Vladimir M Pentkovsky; Alexander A Vassilevski; Eugene V Grishin; Roman G Efremov
Journal:  J Biol Chem       Date:  2013-05-01       Impact factor: 5.157

6.  Characterization of Kbot21 Reveals Novel Side Chain Interactions of Scorpion Toxins Inhibiting Voltage-Gated Potassium Channels.

Authors:  Rym ElFessi-Magouri; Steve Peigneur; Houcemeddine Othman; Najet Srairi-Abid; Mohamed ElAyeb; Jan Tytgat; Riadh Kharrat
Journal:  PLoS One       Date:  2015-09-23       Impact factor: 3.240

Review 7.  From Mollusks to Medicine: A Venomics Approach for the Discovery and Characterization of Therapeutics from Terebridae Peptide Toxins.

Authors:  Aida Verdes; Prachi Anand; Juliette Gorson; Stephen Jannetti; Patrick Kelly; Abba Leffler; Danny Simpson; Girish Ramrattan; Mandë Holford
Journal:  Toxins (Basel)       Date:  2016-04-19       Impact factor: 4.546
  7 in total

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