Literature DB >> 6729660

Treatment of experimental murine candidiasis with liposome-associated amphotericin B.

J Ahrens, J R Graybill, P C Craven, R L Taylor.   

Abstract

Mice were challenged intravenously with Candida albicans, and then treated either with nothing (controls), amphotericin B-desoxycholate (AMB), or amphotericin B associated with liposomes (AMB-lipo). AMB-lipo permitted larger doses of amphotericin B to be given, and also appeared to have no severe toxicity in the animal model. High doses of AMB-lipo were protective, but at equal doses, AMB-lipo was not as effective as commercial AMB.

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Year:  1984        PMID： 6729660     DOI： 10.1080/00362178485380251

Source DB:  PubMed          Journal:  Sabouraudia        ISSN： 0036-2174


  7 in total

Review 1.  Liposomes as drug delivery system in the treatment of infectious diseases. Potential applications and clinical experience.

Authors:  A Coune
Journal:  Infection       Date:  1988 May-Jun       Impact factor: 3.553

2.  Synergistic antifungal activity and reduced toxicity of liposomal amphotericin B combined with gramicidin S or NF.

Authors:  R L Hopfer; R Mehta; G Lopez-Berestein
Journal:  Antimicrob Agents Chemother       Date:  1987-12       Impact factor: 5.191

Review 3.  In vitro and in vivo evaluation of antifungal agents.

Authors:  A Espinel-Ingroff; S Shadomy
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1989-04       Impact factor: 3.267

Review 4.  Carrier effects on biological activity of amphotericin B.

Authors:  J Brajtburg; J Bolard
Journal:  Clin Microbiol Rev       Date:  1996-10       Impact factor: 26.132

5.  Amphotericin B lipid complex therapy of experimental fungal infections in mice.

Authors:  J M Clark; R R Whitney; S J Olsen; R J George; M R Swerdel; L Kunselman; D P Bonner
Journal:  Antimicrob Agents Chemother       Date:  1991-04       Impact factor: 5.191

6.  Dose-dependent antifungal activity and nephrotoxicity of amphotericin B colloidal dispersion in experimental pulmonary aspergillosis.

Authors:  M C Allende; J W Lee; P Francis; K Garrett; H Dollenberg; J Berenguer; C A Lyman; P A Pizzo; T J Walsh
Journal:  Antimicrob Agents Chemother       Date:  1994-03       Impact factor: 5.191

7.  Therapeutic monitoring of experimental invasive pulmonary aspergillosis by ultrafast computerized tomography, a novel, noninvasive method for measuring responses to antifungal therapy.

Authors:  T J Walsh; K Garrett; E Feurerstein; M Girton; M Allende; J Bacher; A Francesconi; R Schaufele; P A Pizzo
Journal:  Antimicrob Agents Chemother       Date:  1995-05       Impact factor: 5.191
  7 in total

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