Literature DB >> 6727666

Chemistry of lipid peroxidation.

N A Porter.   

Abstract

The free radical chemistry of lipid peroxidation is complex. The classical mechanism of autoxidation involving a peroxy radical abstracting hydrogen atom from lipid and oxygen addition to the carbon radical thus formed must be modified to include (1) peroxy radical beta fragmentation and (2) peroxy radical cyclization. A host of diene hydroperoxides, cyclic peroxides, bicyclic peroxides and epoxy alcohols may be formed in free fatty acid or phospholipid autoxidation. The distribution of products and the effects of hydrogen atom donors on product distribution are understandable by referring to a general scheme for autoxidation described in Scheme III and in Ref. 10.

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Year:  1984        PMID： 6727666     DOI： 10.1016/s0076-6879(84)05035-7

Source DB:  PubMed          Journal:  Methods Enzymol        ISSN： 0076-6879            Impact factor:   1.600


  26 in total

1.  The reactivity of human serum albumin toward trans-4-hydroxy-2-nonenal.

Authors:  Qingyuan Liu; David C Simpson; Scott Gronert
Journal:  J Mass Spectrom       Date:  2012-04       Impact factor: 1.982

Review 2.  Therapies targeting lipid peroxidation in traumatic brain injury.

Authors:  Tamil Selvan Anthonymuthu; Elizabeth Megan Kenny; Hülya Bayır
Journal:  Brain Res       Date:  2016-02-10       Impact factor: 3.252

3.  Studies on the metal-ion and lipoxygenase-catalysed breakdown of hydroperoxides using electron-spin-resonance spectroscopy.

Authors:  M J Davies; T F Slater
Journal:  Biochem J       Date:  1987-07-01       Impact factor: 3.857

4.  Tyrosine-lipid peroxide adducts from radical termination: para coupling and intramolecular Diels-Alder cyclization.

Authors:  Roman Shchepin; Matias N Möller; Hye-young H Kim; Duane M Hatch; Silvina Bartesaghi; Balaraman Kalyanaraman; Rafael Radi; Ned A Porter
Journal:  J Am Chem Soc       Date:  2010-11-19       Impact factor: 15.419

5.  Role of glutamate transporters in redox homeostasis of the brain.

Authors:  Stephanie M Robert; Toyin Ogunrinu-Babarinde; Kenneth T Holt; Harald Sontheimer
Journal:  Neurochem Int       Date:  2014-01-10       Impact factor: 3.921

6.  Effects of conjugated linoleic acid on oxygen diffusion-concentration product and depletion in membranes by using electron spin resonance spin-label oximetry.

Authors:  J J Yin; M M Mossoba; J K Kramer; M P Yurawecz; K Eulitz; K M Morehouse; Y Ku
Journal:  Lipids       Date:  1999-10       Impact factor: 1.880

7.  Evaluation of protein oxidation and its association with lipid peroxidation and thyrotropin levels in overt and subclinical hypothyroidism.

Authors:  A Haribabu; V Seshadri Reddy; Ch Pallavi; Aparna R Bitla; Alok Sachan; P Pullaiah; V Suresh; P V L N Srinivasa Rao; M M Suchitra
Journal:  Endocrine       Date:  2012-12-08       Impact factor: 3.633

8.  Methods for imaging and detecting modification of proteins by reactive lipid species.

Authors:  Ashlee N Higdon; Brian P Dranka; Bradford G Hill; Joo-Yeun Oh; Michelle S Johnson; Aimee Landar; Victor M Darley-Usmar
Journal:  Free Radic Biol Med       Date:  2009-05-14       Impact factor: 7.376

9.  Developmental profiles of protective mechanisms of heart against peroxidative injury.

Authors:  D K Das; R M Engelman; D Flansaas; H Otani; J Rousou; R H Breyer
Journal:  Basic Res Cardiol       Date:  1987 Jan-Feb       Impact factor: 17.165

10.  Dietary fat effects on hepatic lipid peroxidation and enzymes of H2O2 metabolism and NADPH generation.

Authors:  L C Chen; G Boissonneault; M G Hayek; C K Chow
Journal:  Lipids       Date:  1993-07       Impact factor: 1.880
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