Literature DB >> 6726648

Serotonergic receptor antagonist from Nandina domestica Thunberg.

N Shoji, A Umeyama, T Takemoto, Y Ohizumi.   

Abstract

A crude methanolic extract of the fruit of Nandina domestica Thunberg strongly inhibits serotonin-induced contractions of the rabbit aorta. The extract of the fruit has been fractionated to afford nantenine (O- methyldomesticine ) as the active agent.

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Year:  1984        PMID: 6726648     DOI: 10.1002/jps.2600730435

Source DB:  PubMed          Journal:  J Pharm Sci        ISSN: 0022-3549            Impact factor:   3.534


  2 in total

1.  A New Route to Azafluoranthene Natural Products via Direct Arylation.

Authors:  Shashikanth Ponnala; Wayne W Harding
Journal:  European J Org Chem       Date:  2013-01-03

2.  Nantenine: an antagonist of the behavioral and physiological effects of MDMA in mice.

Authors:  William E Fantegrossi; Christina Lynn Kiessel; P Tarn Leach; C Van Martin; Rachel Lynn Karabenick; X Chen; Y Ohizumi; Thomas Ullrich; Kenner C Rice; James H Woods
Journal:  Psychopharmacology (Berl)       Date:  2004-01-22       Impact factor: 4.530

  2 in total

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