Literature DB >> 6726249

Comparison of two superfusion systems for study of neurotransmitter release from rat cerebral cortex slices.

E R Korpi, S S Oja.   

Abstract

Depolarization-induced release of [3H]gamma-aminobutyric acid (GABA) and [3H]noradrenaline (NA) from rat cerebral cortex slices was studied in two superfusion systems: one with stationary and the other one with continuously shaken slice compartments. Calcium-dependent depolarization-induced release of GABA and NA could be demonstrated only with shaken slices. GABA, but not NA, could also be released by high K+ media and veratridine from stationary slices. Synaptic transmitter releasing mechanisms are apparently damaged in stationary slices, possibly due to impaired energy metabolism.

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Year:  1984        PMID： 6726249     DOI： 10.1111/j.1471-4159.1984.tb06701.x

Source DB:  PubMed          Journal:  J Neurochem        ISSN： 0022-3042            Impact factor:   5.372


  6 in total

1.  Release of [3H]dopamine from striatal and cerebral cortical slices from rats with thioacetamide-induced hepatic encephalopathy: different responses to stimulation by potassium ions and agonists of ionotropic glutamate receptors.

Authors:  H D Borkowska; S S Oja; P Saransaari; J Albrecht
Journal:  Neurochem Res       Date:  1997-02       Impact factor: 3.996

2.  Properties and glial origin of osmotic-dependent release of taurine from the rat supraoptic nucleus.

Authors:  C Deleuze; A Duvoid; N Hussy
Journal:  J Physiol       Date:  1998-03-01       Impact factor: 5.182

3.  Taurine and GABA release from mouse cerebral cortex slices: effects of structural analogues and drugs.

Authors:  P Kontro; S S Oja
Journal:  Neurochem Res       Date:  1987-05       Impact factor: 3.996

4.  Effect of aminooxyacetic acid on the release of preloaded [3H]GABA and radioactive metabolites from slices of developing mouse brain.

Authors:  S S Oja; P Kontro
Journal:  Neurochem Res       Date:  1988-10       Impact factor: 3.996

5.  Glutamate agonists and [3H]GABA release from rat hippocampal slices: involvement of metabotropic glutamate receptors in the quisqualate-evoked release.

Authors:  R Janáky; V Varga; P Saransaari; S S Oja
Journal:  Neurochem Res       Date:  1994-06       Impact factor: 3.996

6.  Modulation of GABAergic neurotransmission in the brain by dipeptides.

Authors:  V Varga; P Kontro; S S Oja
Journal:  Neurochem Res       Date:  1988-11       Impact factor: 3.996
  6 in total

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