| Literature DB >> 6725947 |
S G Reed, M Barral-Netto, J A Inverso.
Abstract
Highly susceptible mice were infected with Leishmania donovani chagasi and were treated with supernatants, free or encapsulated in liposomes, from concanavalin A-stimulated or unstimulated mouse spleen cell cultures. Treatment consisted of multiple i.v. injections beginning 2 days before to 2 days after infection. Mice treated with lymphokine-rich supernatants encapsulated in liposomes had significantly fewer liver parasites than the control groups, demonstrating in vivo activity of lymphokine against an infectious organism.Entities:
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Year: 1984 PMID： 6725947
Source DB: PubMed Journal: J Immunol ISSN： 0022-1767 Impact factor: 5.422