| Literature DB >> 6725480 |
C Lacroix, G Laine, J P Goulle, J Nouveau.
Abstract
A method for the analysis of isoniazid and acetylisoniazid in plasma or serum has been developed. This report describes a simple, quick and economically optimized reversed-phase high-performance liquid chromatographic assay using a small sample size without solvent extraction step. Isoniazid was condensed with cinnamic aldehyde after trichloroacetic acid deproteinisation. The method correlated well with a fluorimetric procedure. Precision, sensibility and accuracy were good. Common antituberculous drugs did not interfere.Entities:
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Year: 1984 PMID： 6725480
Source DB: PubMed Journal: J Chromatogr