Literature DB >> 6724637

IgG subclasses in collagen-induced arthritis in the rat.

S A Firth, K Morgan, H B Evans, P J Holt.   

Abstract

Using a solid-phase double-antibody radioimmunoassay IgG antibodies to native bovine type II collagen were measured as total IgG and as subclasses of IgG (IgG1, IgG2a, IgG2b, IgG2c ) in arthritic and non-arthritic Sprague-Dawley rats. Statistically significant differences were observed between arthritic and non-arthritic animals for IgG1, IgG2a, IgG2b and total IgG. The significance of these results and their possible relevance to the human disease are discussed.

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Year:  1984        PMID： 6724637     DOI： 10.1016/0165-2478(84)90029-4

Source DB:  PubMed          Journal:  Immunol Lett        ISSN： 0165-2478            Impact factor:   3.685


  7 in total

1.  Antigen inhibition of collagen-induced arthritis is associated with up-regulation of IL-4 mRNA and induction of Ox40 on T cells in draining lymph nodes.

Authors:  L Mattsson; K Lundberg; E Mussener; A Jansson; H Erlandsson Harris; P Larsson
Journal:  Clin Exp Immunol       Date:  2003-02       Impact factor: 4.330

2.  Contribution of the spleen, lymph nodes and bone marrow to the antibody response in collagen-induced arthritis in the rat.

Authors:  J Rahman; N A Staines
Journal:  Clin Exp Immunol       Date:  1991-07       Impact factor: 4.330

3.  Low-affinity antibodies against collagen type II produced by lymph node cells are associated with pathology in collagen-induced arthritis in rats.

Authors:  J Rahman; J Loh; N A Staines
Journal:  Clin Exp Immunol       Date:  1992-06       Impact factor: 4.330

4.  Identification of an immunodominant B-cell epitope in bovine type II collagen and the production of antibodies to type II collagen by immunization with a synthetic peptide representing this epitope.

Authors:  K Morgan; S L Turner; I Reynolds; A H Hajeer; A Brass; J Worthington
Journal:  Immunology       Date:  1992-12       Impact factor: 7.397

5.  Anti-type V collagen humoral immunity in lung transplant primary graft dysfunction.

Authors:  Takekazu Iwata; Alexander Philipovskiy; Amanda J Fisher; Robert G Presson; Masako Chiyo; Jae Lee; Elizabeth Mickler; Gerald N Smith; Irina Petrache; David B Brand; William J Burlingham; Bagavathi Gopalakrishnan; Daniel S Greenspan; Jason D Christie; David S Wilkes
Journal:  J Immunol       Date:  2008-10-15       Impact factor: 5.422

6.  Restricted expression of anti-type II collagen antibody isotypes in mice suppressed for collagen-induced arthritis.

Authors:  T F Kresina; C K Finegan
Journal:  Ann Rheum Dis       Date:  1986-01       Impact factor: 19.103

7.  Genetic susceptibility to murine collagen II autoimmune arthritis. Proposed relationship to the IgG2 autoantibody subclass response, complement C5, major histocompatibility complex (MHC) and non-MHC loci.

Authors:  W C Watson; A S Townes
Journal:  J Exp Med       Date:  1985-12-01       Impact factor: 14.307
  7 in total

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