Literature DB >> 6723933

Pathological changes in the heterologous phase of antibasement membrane antibody mediated disease in the rat.

L C Yong, J Horn.   

Abstract

The immunological and structural changes during the heterologous phase of experimental antibasement membrane antibody mediated disease was sequentially studied in the rat following single i.v. injections of rabbit antibodies to basement membrane antigens prepared from kidney, lung and salivary gland tissues. Although each of the anti-bodies bound strongly to GBM, structural changes were initially subtle accompanied by proteinuria and hematuria. More severe structural changes related to dose and duration of the disease did not appear for several weeks.

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Year:  1984        PMID： 6723933     DOI： 10.1007/BF01982342

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  11 in total

1.  Glomerulonephritis associated with hydrocarbon solvents: mediated by antiglomerular basement membrane antibody.

Authors:  G J Beirne; J T Brennan
Journal:  Arch Environ Health       Date:  1972-11

2.  Experimental pulmonary disease and autoimmune nephritis in the rabbit produced by homologous and heterologous choroid plexus (experimental Goodpasture's syndrome).

Authors:  R M McIntosh; M N Koss; W B Chernack; W R Griswold; P B Copack; R Weil
Journal:  Proc Soc Exp Biol Med       Date:  1974-10

3.  Antigen identification in Goodpasture's syndrome.

Authors:  R M McIntosh; W Griswold
Journal:  Arch Pathol       Date:  1971-11

4.  A glycoprotein that induces nephrotoxic antibody: its isolation and purification from rat glomerular basement membrane.

Authors:  S Shibata; Y Miyakawa; T Naruse; T Nagasawa; T Takuma
Journal:  J Immunol       Date:  1969-03       Impact factor: 5.422

5.  Immunopathologic studies of an experimental model resembling Goodpasture's syndrome.

Authors:  J E Hagadorn; J J Vazquez; T R Kinney
Journal:  Am J Pathol       Date:  1969-10       Impact factor: 4.307

6.  [Goodpasture syndrome and the effects of benzene].

Authors:  G Klavis; W Drommer
Journal:  Arch Toxikol       Date:  1970

7.  Exfoliation of endothelial cytoplasms in nephrotoxic serum nephritis. A study using antiserum against water-soluble glycoprotein isolated from the glomerular basement membrane.

Authors:  S Shibata; H Sakaguchi; T Nagasawa
Journal:  Lab Invest       Date:  1978-02       Impact factor: 5.662

8.  Pulmonary involvements in the initial phase of rat Masugi nephritis.

Authors:  H Shigematsu; Y Kobayashi
Journal:  Virchows Arch B Cell Pathol       Date:  1972

9.  Studies on the renal glomerular basement membrane. Preparation and chemical composition.

Authors:  R G Spiro
Journal:  J Biol Chem       Date:  1967-04-25       Impact factor: 5.157

10.  The human choroid plexus and autoimmune nephritis.

Authors:  R M McIntosh; P Copack; W B Chernack; W R Griswold; R Weil; M N Koss
Journal:  Arch Pathol       Date:  1975-01
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