Literature DB >> 6721466

Effect of inoculum, pH, and medium on the activity of ciprofloxacin against anaerobic bacteria.

M V Borobio, E J Perea.   

Abstract

The in vitro activity of ciprofloxacin against 30 Bacteroides fragilis group, 30 Clostridium, and 30 Peptococcaceae strains was determined by the agar dilution method in two different culture media at three pH and in three inoculum densities. In Wilkins-Chalgren agar the MICs for 90% of the strains were 0.12 micrograms/ml for B. fragilis, 0.5 micrograms/ml for Clostridium spp., and 2 micrograms/ml for Peptococcaceae. The pH and medium composition affected the MICs of ciprofloxacin.

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Year:  1984        PMID： 6721466      PMCID： PMC185513          DOI： 10.1128/AAC.25.3.342

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  8 in total

1.  Activity of ten antimicrobial agents against anaerobic bacteria.

Authors:  J Dubois; J C Pechère; P Turgeon
Journal:  J Antimicrob Chemother       Date:  1978-07       Impact factor: 5.790

2.  N-formimidoyl-thienamycin activity against anaerobes: effect of the inoculum, pH and culture media.

Authors:  M V Borobio; M C Nogales; A Pascual; E J Perea
Journal:  J Antimicrob Chemother       Date:  1981-09       Impact factor: 5.790

3.  Susceptibility of the Bacteroides fragilis group in the United States in 1981.

Authors:  F P Tally; G J Cuchural; N V Jacobus; S L Gorbach; K E Aldridge; T J Cleary; S M Finegold; G B Hill; P B Iannini; R V McCloskey; J P O'Keefe; C L Pierson
Journal:  Antimicrob Agents Chemother       Date:  1983-04       Impact factor: 5.191

4.  In vitro and in vivo activity of DL-8280, a new oxazine derivative.

Authors:  K Sato; Y Matsuura; M Inoue; T Une; Y Osada; H Ogawa; S Mitsuhashi
Journal:  Antimicrob Agents Chemother       Date:  1982-10       Impact factor: 5.191

5.  Novel method for detection of beta-lactamases by using a chromogenic cephalosporin substrate.

Authors:  C H O'Callaghan; A Morris; S M Kirby; A H Shingler
Journal:  Antimicrob Agents Chemother       Date:  1972-04       Impact factor: 5.191

6.  Comparative activities of ciprofloxacin (Bay o 9867), norfloxacin, pipemidic acid, and nalidixic acid.

Authors:  H L Muytjens; J van der Ros-van de Repe; G van Veldhuizen
Journal:  Antimicrob Agents Chemother       Date:  1983-08       Impact factor: 5.191

7.  In vitro activity of ciprofloxacin, norfloxacin and nalidixic acid.

Authors:  A Bauernfeind; C Petermüller
Journal:  Eur J Clin Microbiol       Date:  1983-04       Impact factor: 3.267

8.  In vitro activity of Bay 09867, a new quinoline derivative, compared with those of other antimicrobial agents.

Authors:  R Wise; J M Andrews; L J Edwards
Journal:  Antimicrob Agents Chemother       Date:  1983-04       Impact factor: 5.191
  8 in total
  16 in total

1.  In vitro activity of tosufloxacin, a new quinolone, against respiratory pathogens derived from cystic fibrosis sputum.

Authors:  A G Arguedas; J C Akaniro; H R Stutman; M I Marks
Journal:  Antimicrob Agents Chemother       Date:  1990-11       Impact factor: 5.191

2.  The fluoroquinolones: structures, mechanisms of action and resistance, and spectra of activity in vitro.

Authors:  J S Wolfson; D C Hooper
Journal:  Antimicrob Agents Chemother       Date:  1985-10       Impact factor: 5.191

3.  Effect of pH on in vitro antimicrobial susceptibility of the Bacteroides fragilis group.

Authors:  M E Falagas; L McDermott; D R Snydman
Journal:  Antimicrob Agents Chemother       Date:  1997-09       Impact factor: 5.191

4.  Comparative activity of ciprofloxacin against anaerobic bacteria.

Authors:  V L Sutter; Y Y Kwok; J Bulkacz
Journal:  Antimicrob Agents Chemother       Date:  1985-03       Impact factor: 5.191

5.  Effect of pathological changes of pH, pO2 and pCO2 on the activity of antimicrobial agents in vitro.

Authors:  C König; H P Simmen; J Blaser
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1993-07       Impact factor: 3.267

6.  Ciprofloxacin penetration into extravascular spaces in a rabbit model.

Authors:  K L Nichol; L R Peterson; C E Fasching; D N Gerding
Journal:  Antimicrob Agents Chemother       Date:  1984-12       Impact factor: 5.191

7.  Interactions of ciprofloxacin with clindamycin, metronidazole, cefoxitin, cefotaxime, and mezlocillin against gram-positive and gram-negative anaerobic bacteria.

Authors:  J L Whiting; N Cheng; A W Chow
Journal:  Antimicrob Agents Chemother       Date:  1987-09       Impact factor: 5.191

8.  Comparative activities of eight quinolones against members of the Bacteroides fragilis group.

Authors:  M V Borobio; M Conejo; E Ramirez; A I Suarez; E J Perea
Journal:  Antimicrob Agents Chemother       Date:  1994-06       Impact factor: 5.191

9.  Efficacy of ofloxacin (HOE 280) in a model of subcutaneous abscess: penetration and prevention of abscess formation.

Authors:  M C García Iglesias; E J Perea
Journal:  Infection       Date:  1986       Impact factor: 3.553

Review 10.  Fluorinated quinolones. A review of their mode of action, antimicrobial activity, pharmacokinetics and clinical efficacy.

Authors:  R Janknegt
Journal:  Pharm Weekbl Sci       Date:  1986-02-21
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