Literature DB >> 6717902

Phase II study of lonidamine in inoperable non-small-cell lung cancer.

O Kokron, S Maca, W Scheiner, M De Gregorio, G B Ciottoli.   

Abstract

31 patients with inoperable non-small-cell lung cancer were treated with Lonidamine at daily doses of 450-900 mg orally. Side effects mostly consisted of myalgias, often severe, and gastrointestinal symptoms. Lonidamine was discontinued in 8 patients because of tumor progression and in 2 on account of side effects. 3 partial responses were observed, 2 in patients with epidermoid tumors.

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Year:  1984        PMID: 6717902     DOI: 10.1159/000225893

Source DB:  PubMed          Journal:  Oncology        ISSN: 0030-2414            Impact factor:   2.935


  1 in total

1.  Phase II study of lonidamine in non-small cell lung cancer: final report.

Authors:  O Kokron; S Maca; M De Gregorio; G B Ciottoli
Journal:  Br J Cancer       Date:  1990-02       Impact factor: 7.640

  1 in total

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