Literature DB >> 6717724

[Intramedullary astrocytoma and ependymoma in the adult. Do therapeutic tactics influence the long-term results? Evaluation of 23 surgically treated cases and discussion of the literature].

F X Roux, A Rey, P Lecoz, B George, C Thurel, J Cophignon, J Mikol.   

Abstract

The authors tried to determine the best treatment of intramedullary tumors nowadays. They studied a personal series of 23 intraspinal ependymomas and astrocytomas. 15 patients had a mean long term follow-up of 5 1/2 years. Among these, only patients with ependymomas were clinically cured or dramatically improved (30%). On the contrary, no patients operated on an astrocytoma received benefit of the surgical procedure. This study was compared to most of the recent series of the literature , the results of which are superimposable . Concerning an intraspinal ependymoma, a logical attitude is to proceed, under optic magnification, to the most complete excision as possible, as long as a well individualized plan of cleavage is visible. Radiotherapy is indicated only in case of incomplete excision or recidive. Concerning an astrocytoma, a total excision is almost always impossible since it is an infiltrating tumor. It appears more dangerous than advantageous to try to take off as much tumor as possible. Radiotherapy appears inefficient.

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Year:  1984        PMID: 6717724

Source DB:  PubMed          Journal:  Neurochirurgie        ISSN: 0028-3770            Impact factor:   1.553


  4 in total

1.  Surgery of intramedullary spinal cord tumours.

Authors:  J Brotchi; J Noterman; D Baleriaux
Journal:  Acta Neurochir (Wien)       Date:  1992       Impact factor: 2.216

Review 2.  Chemotherapy for intramedullary spinal cord tumors.

Authors:  C Balmaceda
Journal:  J Neurooncol       Date:  2000-05       Impact factor: 4.130

3.  Intramedullary astrocytomas and ependymomas in the pediatric age group: a retrospective study.

Authors:  G Innocenzi; A Raco; G Cantore; A J Raimondi
Journal:  Childs Nerv Syst       Date:  1996-12       Impact factor: 1.475

4.  Surgical treatment of intramedullary tumors (spinal cord and medulla oblongata). Analysis of 16 cases.

Authors:  A Ahyai; U Woerner; E Markakis
Journal:  Neurosurg Rev       Date:  1990       Impact factor: 3.042

  4 in total

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