[Effect of emotional stress on the system of hemostasis in patients with coronary arteriosclerosis].

Under conditions of experimentally induced psychic stress, the changes were studied in the activity of the sympatheticoadrenal system and the thrombocytic-vascular and the plasmic links of the hemostatic system. Ninety-seven men aged 35-61 years and suffering from coronary heart disease without hypertension and circulation insufficiency were studied. The diagnosis of coronary atherosclerosis was confirmed by selestive coronary angiography. Hypercatecholaminemia and a hypercoagulatory state were elicited prior to the investigation. According to the adaptive-protective activation of the anticoagulation system, in particular heparin activation, the patients were divided into two groups: a favourable one, characterized by the adequate protective activation of the anticlotting system, and an unfavourable one, characterized by the depression of the anticoagulation system and the depletion of the sympatheticoadrenal system.