Literature DB >> 67166

Immune mechanisms in leukemia role of the Ia antigens.

O A Lukasewycz, J A Frelinger.   

Abstract

We have shown that the selective removal of cells possessing Ia determinants coded by the I-A, I-B, and I-J regions of the H-2 gene complex completely abrogates the protective capacity of nylon-wool-purified T lymphocytes against leukemic challenge. This suggests that the Ia antigen bearing T cells play an important role in tumor immunity.

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Year:  1977        PMID： 67166      PMCID： PMC2180632          DOI： 10.1084/jem.145.4.1077

Source DB:  PubMed          Journal:  J Exp Med        ISSN： 0022-1007            Impact factor:   14.307


  20 in total

1.  Immune mechanisms in leukemia: evaluation of immunocompetent cell populations.

Authors:  O A Lukasewycz; D Martinez; W H Murphy
Journal:  J Immunol       Date:  1975-05       Impact factor: 5.422

2.  Ia alloantigen(s) detected on thymocytes by use of a fluorescence-activated cell sorter.

Authors:  C G Fathman; J L Cone; S O Sharrow; H Tyrer; D H Sachs
Journal:  J Immunol       Date:  1975-08       Impact factor: 5.422

3.  Immune mechanisms in leukemia: protective capacity of the major lymphoid cell compartments.

Authors:  O A Lukasewycz; P S Duffey; W H Murphy
Journal:  J Immunol       Date:  1976-04       Impact factor: 5.422

4.  Immune mechanisms in leukemia: suppression of cellular immunity by drugs and x-irradiation.

Authors:  D Martinez; O A Lukasewycz; W H Murphy
Journal:  J Immunol       Date:  1975-09       Impact factor: 5.422

5.  Immune mechanisms in leukemia: suppression of cellular immunity by starvation.

Authors:  D Martinez; S Cox; O A Lukassewycz; W H Murphy
Journal:  J Natl Cancer Inst       Date:  1975-10       Impact factor: 13.506

6.  Functional subclasses of T-lymphocytes bearing different Ly antigens. I. The generation of functionally distinct T-cell subclasses is a differentiative process independent of antigen.

Authors:  H Cantor; E A Boyse
Journal:  J Exp Med       Date:  1975-06-01       Impact factor: 14.307

7.  A new I subregion (I-J) marked by a locus (Ia-4) controlling surface determinants on suppressor T lymphocytes.

Authors:  D B Murphy; L A Herzenberg; K Okumura; L A Herzenberg; H O McDevitt
Journal:  J Exp Med       Date:  1976-09-01       Impact factor: 14.307

8.  Selective expression of H-2 (i-region) loci controlling determinants on helper and suppressor T lymphocytes.

Authors:  K Okumura; L A Herzenberg; D B Murphy; H O McDevitt; L A Herzenberg
Journal:  J Exp Med       Date:  1976-09-01       Impact factor: 14.307

9.  The Fc receptor on thymus-derived lymphocytes: II. Mitogen responsiveness of T lymphocytes bearing the Fc receptor.

Authors:  R D Stout; L A Herzenberg
Journal:  J Exp Med       Date:  1975-11-01       Impact factor: 14.307

10.  Effects of anti-Ia sera on mitogenic responses. II. Differential expression of the Ia marker on phytohemagglutinin and concanavalin A-reactive T cells.

Authors:  J E Niederhuber; J A Frelinger; M S Dine; P Shoffner; E Dugan; D C Shreffler
Journal:  J Exp Med       Date:  1976-02-01       Impact factor: 14.307
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