Literature DB >> 6716254

Synthesis and antibacterial activity of some 5-nitro-3-phenyliminoindol-2(3H)-ones and their N-Mannich bases.

R W Daisley, V K Shah.   

Abstract

The antimicrobial and antifungal activities of a series of 5-nitro-3-phenyliminoindol-2(3H)-ones and their 1-piperidinomethyl analogues (N-Mannich bases) were investigated. Growth inhibition of Gram-positive bacteria was observed with little or no activity against Gram-negative bacteria. Antifungal activity was absent. The syntheses were accomplished from 5-nitroindol-2,3-dione by condensation with the appropriate aniline followed by formation of the N-Mannich base.

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Year:  1984        PMID： 6716254     DOI： 10.1002/jps.2600730333

Source DB:  PubMed          Journal:  J Pharm Sci        ISSN： 0022-3549            Impact factor:   3.534


  3 in total

1.  Synthesis characterization and biological activity study of new schiff and mannich bases and some metal complexes derived from isatin and dithiooxamide.

Authors:  Ahlam J Abdulghani; Nada M Abbas
Journal:  Bioinorg Chem Appl       Date:  2011-05-15       Impact factor: 7.778

2.  Crystal structure of 4-({(1E,2E)-3-[3-(4-fluoro-phen-yl)-1-isopropyl-1H-indol-2-yl]allyl-idene}amino)-1H-1,2,4-triazole-5(4H)-thione.

Authors:  Ajaykumar D Kulkarni; Md Lutfor Rahman; Mashitah Mohd Yusoff; Huey Chong Kwong; Ching Kheng Quah
Journal:  Acta Crystallogr E Crystallogr Commun       Date:  2015-11-25

3.  Crystal structure of 3-{5-[3-(4-fluoro-phen-yl)-1-isopropyl-1H-indol-2-yl]-1H-pyrazol-1-yl}indolin-2-one ethanol monosolvate.

Authors:  Md Lutfor Rahman; Ajaykumar D Kulkarni; Mashitah Mohd Yusoff; Huey Chong Kwong; Ching Kheng Quah
Journal:  Acta Crystallogr E Crystallogr Commun       Date:  2016-02-03
  3 in total

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