Literature DB >> 6715009

Erythroid precursors cultured from adult mice are sensitive to H2O2 toxicity.

M F Grasset, J P Blanchet.   

Abstract

The growth of late erythroid precursors (CFU-Es) from adult bone marrow is inhibited when Iscove 's modified Dulbecco's medium supplied in liquid form is used. Catalase and other H2O2 destroying compounds restore the capacity of culture medium to support colony development. However early precursors from adult bone marrow and fetal liver CFU-Es were resistant to H2O2.

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Year:  1984        PMID: 6715009     DOI: 10.1007/bf02618592

Source DB:  PubMed          Journal:  In Vitro        ISSN: 0073-5655


  5 in total

1.  Induction of colonies of hemoglobin-synthesizing cells by erythropoietin in vitro.

Authors:  J R Stephenson; A A Axelrad; D L McLeod; M M Shreeve
Journal:  Proc Natl Acad Sci U S A       Date:  1971-07       Impact factor: 11.205

2.  Clonal growth of lymphoid cells in serum-free media requires elimination of H2O2 toxicity.

Authors:  F J Darfler; P A Insel
Journal:  J Cell Physiol       Date:  1983-04       Impact factor: 6.384

3.  Induction of globin mRNA accumulation by hemin in cultured erythroleukemic cells.

Authors:  J Ross; D Sautner
Journal:  Cell       Date:  1976-08       Impact factor: 41.582

4.  Comparison of the effects of hydrogen peroxide and x-ray irradiation on toxicity, mutation, and DNA damage/repair in mammalian cells (V-79).

Authors:  M O Bradley; L C Erickson
Journal:  Biochim Biophys Acta       Date:  1981-06-26

5.  Identification of hydrogen peroxide as a photoproduct toxic to human cells in tissue-culture medium irradiated with "daylight" fluorescent light.

Authors:  R J Wang; B R Nixon
Journal:  In Vitro       Date:  1978-08
  5 in total

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