Literature DB >> 6714423

The isozyme pattern of glutathione S-transferases in rat heart.

T Ishikawa, H Sies.   

Abstract

The isozyme pattern of glutathione S-transferases of rat heart differs markedly from that of liver. Heart lacks the majority of basic isozymes recognized in rat liver, and isoelectric focusing of glutathione S-transferases obtained from affinity chromatography on S-hexylglutathione-linked Sepharose 6B revealed that 3 major acidic isozymes with pI values of 6.8, 6.3 and 4.9 are present in heart, at least two of which were not found in liver. In addition, multiple bands were found in the pI range 5.0-5.5 for glutathione S-transferase activity and protein staining.

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Year:  1984        PMID： 6714423     DOI： 10.1016/0014-5793(84)80309-9

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  6 in total

1.  A proposed mechanism of resistance to cyclophosphamide and phosphoramide mustard in a Yoshida cell line in vitro.

Authors:  A T McGown; B W Fox
Journal:  Cancer Chemother Pharmacol       Date:  1986       Impact factor: 3.333

2.  Use of immuno-blot techniques to discriminate between the glutathione S-transferase Yf, Yk, Ya, Yn/Yb and Yc subunits and to study their distribution in extrahepatic tissues. Evidence for three immunochemically distinct groups of transferase in the rat.

Authors:  J D Hayes; T J Mantle
Journal:  Biochem J       Date:  1986-02-01       Impact factor: 3.857

3.  Isoenzymes of glutathione transferase in rat kidney cytosol.

Authors:  C Guthenberg; H Jensson; L Nyström; E Osterlund; M K Tahir; B Mannervik
Journal:  Biochem J       Date:  1985-09-15       Impact factor: 3.857

4.  Metabolism of ethanol and carcinogens by glutathione transferases.

Authors:  P S Bora; C A Spilburg; L G Lange
Journal:  Proc Natl Acad Sci U S A       Date:  1989-06       Impact factor: 11.205

5.  Glutathione S-transferases in rat olfactory epithelium: purification, molecular properties and odorant biotransformation.

Authors:  N Ben-Arie; M Khen; D Lancet
Journal:  Biochem J       Date:  1993-06-01       Impact factor: 3.857

6.  Nuclear shield: a multi-enzyme task-force for nucleus protection.

Authors:  Raffaele Fabrini; Alessio Bocedi; Valentina Pallottini; Lorena Canuti; Michele De Canio; Andrea Urbani; Valeria Marzano; Tommaso Cornetta; Pasquale Stano; Anna Giovanetti; Lorenzo Stella; Antonella Canini; Giorgio Federici; Giorgio Ricci
Journal:  PLoS One       Date:  2010-12-10       Impact factor: 3.240
  6 in total

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