Literature DB >> 6713639

Ultrastructural localization of aluminum in patients with dialysis-associated osteomalacia.

A H Verbueken, F L Van de Vyver, R E Van Grieken, G J Paulus, W J Visser, P D'Haese, M E De Broe.   

Abstract

Using laser microprobe mass analysis, we studied the ultrastructural localization of aluminum in liver and bone tissue of chronic-hemodialysis patients with proven aluminum-induced osteomalacia. In the liver, aluminum was observed to be almost exclusively associated with iron. Detectable aluminum and large amounts of iron were found in lysosomes of both hepatocytes and Kupffer cells. In bone, aluminum was localized at the osteoid/calcified-bone interface and also was associated with iron in some cases.

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Year:  1984        PMID： 6713639

Source DB:  PubMed          Journal:  Clin Chem        ISSN： 0009-9147            Impact factor:   8.327


  7 in total

1.  Voltage gating in VDAC is markedly inhibited by micromolar quantities of aluminum.

Authors:  E T Dill; M J Holden; M Colombini
Journal:  J Membr Biol       Date:  1987       Impact factor: 1.843

2.  Effects of aluminum(III), chromium(III), and iron(III) on the rate of dissolution of calcium hydroxyapatite crystals in the absence and presence of the chelating agent desferrioxamine.

Authors:  M R Christoffersen; H C Thyregod; J Christoffersen
Journal:  Calcif Tissue Int       Date:  1987-07       Impact factor: 4.333

3.  The effect of aluminum on the rate of dissolution of calcium hydroxyapatite--a contribution to the understanding of aluminum-induced bone diseases.

Authors:  M R Christoffersen; J Christoffersen
Journal:  Calcif Tissue Int       Date:  1985-12       Impact factor: 4.333

4.  Use of laser microprobe mass analysis (LAMMA) for localizing multiple elements in soft and hard tissues.

Authors:  A H Verbueken; F L Van de Vyver; W J Visser; F Roels; R E Van Grieken; M E De Broe
Journal:  Biol Trace Elem Res       Date:  1987-08       Impact factor: 3.738

Review 5.  [Aluminum toxicity].

Authors:  H V Henning
Journal:  Klin Wochenschr       Date:  1989-12-15

6.  Hydrogeochemical studies for Al, F and Fe in waters supplying haemodialysis units in the Trent region, U.K.

Authors:  A P Cameron; P R Ineson
Journal:  Environ Geochem Health       Date:  1986-12       Impact factor: 4.609

Review 7.  Metabolism and possible health effects of aluminum.

Authors:  P O Ganrot
Journal:  Environ Health Perspect       Date:  1986-03       Impact factor: 9.031
  7 in total

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