Literature DB >> 6713206

Enhanced preganglionic sympathetic nerve responses in spontaneously hypertensive rats.

S F Morrison, D Whitehorn.   

Abstract

Sympathetic nerve responses to posterior hypothalamic stimulation were recorded from the preceliac splanchnic nerve in spontaneously hypertensive rats (SHR) and normotensive, Wistar-Kyoto rats (WKY) following interruption of the baroreceptor reflex. Responses to identical stimulation were then recorded following ganglionic blockade with hexamethonium. The enhanced preganglionic sympathetic nerve responses measured in SHR indicate that the sympathetic hyperresponsiveness strain occurs, at least in part, at a site within the central nervous system.

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Year:  1984        PMID： 6713206     DOI： 10.1016/0006-8993(84)90522-5

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  7 in total

1.  Protein kinase CK2 increases glutamatergic input in the hypothalamus and sympathetic vasomotor tone in hypertension.

Authors:  Zeng-You Ye; De-Pei Li; Li Li; Hui-Lin Pan
Journal:  J Neurosci       Date:  2011-06-01       Impact factor: 6.167

2.  Endogenous AT1 receptor-protein kinase C activity in the hypothalamus augments glutamatergic input and sympathetic outflow in hypertension.

Authors:  Huijie Ma; Shao-Rui Chen; Hong Chen; Hui-Lin Pan
Journal:  J Physiol       Date:  2019-07-15       Impact factor: 5.182

3.  Development of the hypersecretory phenotype in the population of adrenal chromaffin cells from prehypertensive SHRs.

Authors:  Johanna Guadalupe Peña Del Castillo; Pedro Segura-Chama; Ruth Rincón-Heredia; Diana Millán-Aldaco; Yolanda Giménez-Molina; José Villanueva; Luis Miguel Gutiérrez; Arturo Hernández-Cruz
Journal:  Pflugers Arch       Date:  2021-09-11       Impact factor: 3.657

4.  Increased angiotensin II binding affinity in the nucleus tractus solitarius of spontaneously hypertensive rats.

Authors:  L M Plunkett; J M Saavedra
Journal:  Proc Natl Acad Sci U S A       Date:  1985-11       Impact factor: 11.205

Review 5.  The abnormalities of adrenomedullary hormonal system in genetic hypertension: Their contribution to altered regulation of blood pressure.

Authors:  A Vavřínová; M Behuliak; I Vaněčková; J Zicha
Journal:  Physiol Res       Date:  2021-05-12       Impact factor: 1.881

6.  Impaired Kv7 channel activity in the central amygdala contributes to elevated sympathetic outflow in hypertension.

Authors:  Zhao-Fu Sheng; Hua Zhang; PeiRu Zheng; Shanyan Chen; Zezong Gu; Jing-Jing Zhou; Jeffery G Phaup; Hui-Ming Chang; Edward T H Yeh; Hui-Lin Pan; De-Pei Li
Journal:  Cardiovasc Res       Date:  2022-01-29       Impact factor: 13.081

7.  Increased intrinsic excitability of muscle vasoconstrictor preganglionic neurons may contribute to the elevated sympathetic activity in hypertensive rats.

Authors:  Linford J B Briant; Alexey O Stalbovskiy; Matthew F Nolan; Alan R Champneys; Anthony E Pickering
Journal:  J Neurophysiol       Date:  2014-08-13       Impact factor: 2.714
  7 in total

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