Literature DB >> 671264

Effect of changes in intercompartment rate constants on drug removal during hemoperfusion.

T P Gibson, A J Atkinson.   

Abstract

A computer simulation of the effect of changing intercompartment clearance rates on drug removal during hemoperfusion was undertaken. As intercompartment clearance slowed, the fall in plasma levels increased and postperfusion rebound increased, but the total drug removed decreased.

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Year:  1978        PMID： 671264     DOI： 10.1002/jps.2600670844

Source DB:  PubMed          Journal:  J Pharm Sci        ISSN： 0022-3549            Impact factor:   3.534


  2 in total

Review 1.  The quinidine-digoxin interaction in perspective.

Authors:  B Fichtl; W Doering
Journal:  Clin Pharmacokinet       Date:  1983 Mar-Apr       Impact factor: 6.447

2.  Analysis of the contributions of permeability and flow of intercompartmental clearance.

Authors:  G P Stec; A J Atkinson
Journal:  J Pharmacokinet Biopharm       Date:  1981-04
  2 in total

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