Literature DB >> 6711781

Non-parenteral postoperative analgesia. A comparison of sublingual buprenorphine and morphine sulphate (slow release) tablets.

D R Derbyshire, M Vater, C I Maile, I M Larsson, A R Aitkenhead, G Smith.   

Abstract

Sixty-nine patients undergoing upper and lower abdominal surgery were studied after operation to compare the analgesic effects of sublingual buprenorphine (0.4 mg) and slow release morphine sulphate tablets (MST, 20 mg) given 6 hourly in a double-blind, double-dummy trial. Both MST and buprenorphine produced satisfactory postoperative analgesia but the linear analogue pain scores were significantly lower on the second post operative day with MST.

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Year:  1984        PMID: 6711781     DOI: 10.1111/j.1365-2044.1984.tb07271.x

Source DB:  PubMed          Journal:  Anaesthesia        ISSN: 0003-2409            Impact factor:   6.955


  3 in total

Review 1.  Clinical pharmacokinetics of drug administered buccally and sublingually.

Authors:  J G Motwani; B J Lipworth
Journal:  Clin Pharmacokinet       Date:  1991-08       Impact factor: 6.447

2.  A comparison of regularly dosed oral morphine and on-demand intramuscular morphine in the treatment of postsurgical pain.

Authors:  J P McCormack; C B Warriner; M Levine; N Glick
Journal:  Can J Anaesth       Date:  1993-09       Impact factor: 5.063

3.  [Application procedures and dosage recommendations for postoperative analgesia.].

Authors:  W Dick; R Janik
Journal:  Schmerz       Date:  1988-03       Impact factor: 1.107

  3 in total

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