Literature DB >> 67106

Specificity of the Tumor-specific transplantation antigen induced by JC virus, a human polyomavirus.

B L Padgett, J M Hunt, D L Walker.   

Abstract

The specificity of the tumor-specific transplantation antigen (TSTA) induced by JC virus was investigated by cross protection tests in weanling hamsters. Hamsters immunized with JC virus, BK virus, or SV40 were challenged 5 weeks later with known numbers of JC virus- or SV40-induced hamster tumor cells. Both the JC virus-immune and the SV40-immune hamsters showed resistance to challenge with homologous but not heterologous tumor cells, and the BK virus-immune hamsters were not resistant to either heterologous tumor cell. The TSTA induced by JC virus did not cross-react with that induced by SV40.

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Year:  1977        PMID: 67106     DOI: 10.1159/000148893

Source DB:  PubMed          Journal:  Intervirology        ISSN: 0300-5526            Impact factor:   1.763


  2 in total

1.  Common methionine-tryptic peptides near the amino-terminal end of primate papovavirus tumor antigens.

Authors:  D T Simmons; M A Martin
Journal:  Proc Natl Acad Sci U S A       Date:  1978-03       Impact factor: 11.205

2.  Cell-mediated immune reaction against BK virus-transformed cells.

Authors:  R Mäntyjärvi; H Karjalainen; M Laaksonen
Journal:  Cancer Immunol Immunother       Date:  1984       Impact factor: 6.968

  2 in total

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