| Literature DB >> 67106 |
B L Padgett, J M Hunt, D L Walker.
Abstract
The specificity of the tumor-specific transplantation antigen (TSTA) induced by JC virus was investigated by cross protection tests in weanling hamsters. Hamsters immunized with JC virus, BK virus, or SV40 were challenged 5 weeks later with known numbers of JC virus- or SV40-induced hamster tumor cells. Both the JC virus-immune and the SV40-immune hamsters showed resistance to challenge with homologous but not heterologous tumor cells, and the BK virus-immune hamsters were not resistant to either heterologous tumor cell. The TSTA induced by JC virus did not cross-react with that induced by SV40.Entities:
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Year: 1977 PMID: 67106 DOI: 10.1159/000148893
Source DB: PubMed Journal: Intervirology ISSN: 0300-5526 Impact factor: 1.763