Literature DB >> 6707659

A comparison of changes in the nucleus basalis and locus caeruleus in Alzheimer's disease.

D M Mann, P O Yates, B Marcyniuk.   

Abstract

In 22 patients with Alzheimer's disease loss of neurons from the nucleus basalis of Meynert and locus caeruleus averaged 58% and 71% respectively with nucleolar volume being reduced by 30% in both. These changes were greater in those patients under 80 years of age and in such patients damage to the locus was more severe than that to the nucleus basalis. In older patients (over 80 years) changes were similar in extent in both regions.

Entities:  

Mesh：

Year:  1984        PMID： 6707659      PMCID： PMC1027693          DOI： 10.1136/jnnp.47.2.201

Source DB:  PubMed          Journal:  J Neurol Neurosurg Psychiatry        ISSN： 0022-3050            Impact factor:   10.154


  21 in total

1.  Accelerated ageing or selective neuronal loss as an important cause of dementia?

Authors:  D M Bowen; P White; J A Spillane; M J Goodhardt; G Curzon; P Iwangoff; W Meier-Ruge; A N Davison
Journal:  Lancet       Date:  1979-01-06       Impact factor: 79.321

2.  Reduced dopamine-beta-hydroxylase activity in Alzheimer's disease.

Authors:  A J Cross; T J Crow; E K Perry; R H Perry; G Blessed; B E Tomlinson
Journal:  Br Med J (Clin Res Ed)       Date:  1981-01-10

3.  Cell loss in the locus coeruleus in senile dementia of Alzheimer type.

Authors:  B E Tomlinson; D Irving; G Blessed
Journal:  J Neurol Sci       Date:  1981-03       Impact factor: 3.181

4.  Neurotransmitter-related enzymes in senile dementia of the Alzheimer type.

Authors:  P Davies
Journal:  Brain Res       Date:  1979-08-03       Impact factor: 3.252

5.  Neurotransmitter enzyme abnormalities in senile dementia. Choline acetyltransferase and glutamic acid decarboxylase activities in necropsy brain tissue.

Authors:  E K Perry; P H Gibson; G Blessed; R H Perry; B E Tomlinson
Journal:  J Neurol Sci       Date:  1977-11       Impact factor: 3.181

6.  Changes in the monoamine containing neurones of the human CNS in senile dementia.

Authors:  D M Mann; J Lincoln; P O Yates; J E Stamp; S Toper
Journal:  Br J Psychiatry       Date:  1980-06       Impact factor: 9.319

7.  Computed tomography in the elderly. 2. Senile dementia: diagnosis and functional impairment.

Authors:  R J Jacoby; R Levy
Journal:  Br J Psychiatry       Date:  1980-03       Impact factor: 9.319

8.  Correlation of cholinergic abnormalities with senile plaques and mental test scores in senile dementia.

Authors:  E K Perry; B E Tomlinson; G Blessed; K Bergmann; P H Gibson; R H Perry
Journal:  Br Med J       Date:  1978-11-25

9.  Neocortical cholinergic neurons in elderly people.

Authors:  P White; C R Hiley; M J Goodhardt; L H Carrasco; J P Keet; I E Williams; D M Bowen
Journal:  Lancet       Date:  1977-03-26       Impact factor: 79.321

10.  A quantitative study of cerebral atrophy in old age and senile dementia.

Authors:  B M Hubbard; J M Anderson
Journal:  J Neurol Sci       Date:  1981-04       Impact factor: 3.181
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  21 in total

1.  Recovery and measurement of RNA in Alzheimer's disease by molecular hybridisation.

Authors:  G R Taylor; G I Carter; T J Crow; J A Johnson; A F Fairbairn; E K Perry; R H Perry
Journal:  J Neurol Neurosurg Psychiatry       Date:  1987-03       Impact factor: 10.154

Review 2.  Activating the damaged basal forebrain cholinergic system: tonic stimulation versus signal amplification.

Authors:  M Sarter; J P Bruno; P Dudchenko
Journal:  Psychopharmacology (Berl)       Date:  1990       Impact factor: 4.530

Review 3.  Cognitive Impairment, Neuroimaging, and Alzheimer Neuropathology in Mouse Models of Down Syndrome.

Authors:  Eric D Hamlett; Heather A Boger; Aurélie Ledreux; Christy M Kelley; Elliott J Mufson; Maria F Falangola; David N Guilfoyle; Ralph A Nixon; David Patterson; Nathan Duval; Ann-Charlotte E Granholm
Journal:  Curr Alzheimer Res       Date:  2016       Impact factor: 3.498

4.  Immunodetection of the amyloid P component in Alzheimer's disease.

Authors:  T Duong; E C Pommier; A B Scheibel
Journal:  Acta Neuropathol       Date:  1989       Impact factor: 17.088

5.  Nucleus raphe dorsalis in parkinsonism-dementia complex of Guam.

Authors:  T Yamamoto; A Hirano
Journal:  Acta Neuropathol       Date:  1985       Impact factor: 17.088

Review 6.  Locus Coeruleus Modulates Neuroinflammation in Parkinsonism and Dementia.

Authors:  Filippo Sean Giorgi; Francesca Biagioni; Alessandro Galgani; Nicola Pavese; Gloria Lazzeri; Francesco Fornai
Journal:  Int J Mol Sci       Date:  2020-11-16       Impact factor: 5.923

7.  Ablation of the locus coeruleus increases oxidative stress in tg-2576 transgenic but not wild-type mice.

Authors:  Orest Hurko; Kurt Boudonck; Cathleen Gonzales; Zoe A Hughes; J Steve Jacobsen; Peter H Reinhart; Daniel Crowther
Journal:  Int J Alzheimers Dis       Date:  2010-10-11

8.  Morphological and biochemical changes in the cholinergic and monoaminergic systems in Alzheimer-type dementia.

Authors:  Y Ichimiya; H Arai; K Kosaka; R Iizuka
Journal:  Acta Neuropathol       Date:  1986       Impact factor: 17.088

Review 9.  Dysfunctional Sensory Modalities, Locus Coeruleus, and Basal Forebrain: Early Determinants that Promote Neuropathogenesis of Cognitive and Memory Decline and Alzheimer's Disease.

Authors:  Mak Adam Daulatzai
Journal:  Neurotox Res       Date:  2016-06-23       Impact factor: 3.911

10.  Functional neuroanatomy of the noradrenergic locus coeruleus: its roles in the regulation of arousal and autonomic function part II: physiological and pharmacological manipulations and pathological alterations of locus coeruleus activity in humans.

Authors:  E R Samuels; E Szabadi
Journal:  Curr Neuropharmacol       Date:  2008-09       Impact factor: 7.363
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