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Literature DB >> 67074

Banding and spiralization of human metaphase chromosomes.

Abstract

A new technique is described which produces spiralization of human metaphase chromosomes. The important feature is heat followed by trypsin treatment. By varying conditions, it is possible to produce bands, spirals and intermediate stages. This provides a new approach to the understanding of banding and chromosome structure.

Entities: Species

Mesh：

Substances：
Trypsin

Year: 1977 PMID： 67074 DOI： 10.1007/BF00273253

Source DB: PubMed Journal: Hum Genet ISSN： 0340-6717 Impact factor: 4.132

15 in total

1. ELECTRON MICROGRAPHIC STUDIES OF THE EXPANDED AND UNCOILED CHROMOSOMES FROM HUMAN LEUKOCYTES.

Authors: E E OSGOOD; D P JENKINS; R BROOKS; R K LAWSON
Journal: Ann N Y Acad Sci Date: 1964-02-28 Impact factor: 5.691

2. Mechanisms of chromosome banding. II. Evidence that histones are not involved.

Authors: D E Comings; E Avelino
Journal: Exp Cell Res Date: 1974-05 Impact factor: 3.905

3. G-banding and chromosome structure.

Authors: J J Yunis; O Sanchez
Journal: Chromosoma Date: 1973 Impact factor: 4.316

4. Correlation of the fluorescent banding pattern and ultrastructure of a human chromosome.

Authors: H M Golomb; G F Bahr
Journal: Exp Cell Res Date: 1974-03-15 Impact factor: 3.905

5. The ultrastructure of human mitotic chromosomes and interphase nuclei treated by Giemsa banding techniques.

Authors: F Ruzicka; H G Schwarzacher
Journal: Chromosoma Date: 1974 Impact factor: 4.316

6. Mechanisms involved in the banding of chromosomes with quinacrine and Giemsa. I. The effects of fixation in methanol-acetic acid.

Authors: A T Sumner; H J Evans; R A Buckland
Journal: Exp Cell Res Date: 1973-09 Impact factor: 3.905

Banding and spiralization of human metaphase chromosomes.

1. ELECTRON MICROGRAPHIC STUDIES OF THE EXPANDED AND UNCOILED CHROMOSOMES FROM HUMAN LEUKOCYTES.

2. Mechanisms of chromosome banding. II. Evidence that histones are not involved.

3. G-banding and chromosome structure.

4. Correlation of the fluorescent banding pattern and ultrastructure of a human chromosome.

5. The ultrastructure of human mitotic chromosomes and interphase nuclei treated by Giemsa banding techniques.

6. Mechanisms involved in the banding of chromosomes with quinacrine and Giemsa. I. The effects of fixation in methanol-acetic acid.

7. Banding patterns of Chinese hamster chromosomes revealed by new techniques.

8. Quantitative constraints in the arrangement of human DNA.

9. [Ultrastructure of human metaphase chromosomes].

10. Observations on human somatic chromosomes treated with hyaluronidase.

1. Induction of uncoiled chromosomes by vibration.