Literature DB >> 6706429

llC labelling of a protein: concanavalin A.

G Berger, M Mazière, C Prenant, J Sastre, D Comar.   

Abstract

A method is described for the 11C labelling of a phytoagglutinin, concanavalin A, involving reductive methylation by formaldehyde and sodium cyanoborohydride. The reaction mixture is then chromatographed by gel permeation. The quantities (20-80 mCi) and specific activities (20-170 mCi/mg) obtained are such that a practical application of the method is possible. No evidence was found, however, of any preferential uptake of concanavalin A by Krebs II ascite cells in Swiss mice.

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Year:  1984        PMID: 6706429     DOI: 10.1016/0020-708x(84)90188-1

Source DB:  PubMed          Journal:  Int J Appl Radiat Isot        ISSN: 0020-708X


  2 in total

1.  A comparison of the sensitivity of PET and NMR for in vivo quantitative metabolic imaging.

Authors:  A M Paans; W Vaalburg; M G Woldring
Journal:  Eur J Nucl Med       Date:  1985

2.  Proof of principle for the use of 11C-labelled peptides in tumour diagnosis with PET.

Authors:  G Henriksen; M Schottelius; T Poethko; A Hauser; I Wolf; M Schwaiger; Hans-Jürgen Wester
Journal:  Eur J Nucl Med Mol Imaging       Date:  2004-08-10       Impact factor: 9.236

  2 in total

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