Literature DB >> 6705260

Problems of detecting mosaicism in skin. A case of trisomy 8 mosaicism illustrating the advantages of in situ tissue culture.

S E Procter, J L Watt, D J Lloyd, P Duffty.   

Abstract

A case of mosaic trisomy 8 is described and the accuracy of flask culture and in situ culture techniques in detecting chromosomal mosaicism in tissues discussed. The advantages of the in situ method are illustrated and the importance of mixed colonies in defining mosaicism highlighted. The implications for prenatal diagnosis of mosaicism are pointed out.

Mesh：

Year:  1984        PMID： 6705260     DOI： 10.1111/j.1399-0004.1984.tb01989.x

Source DB:  PubMed          Journal:  Clin Genet        ISSN： 0009-9163            Impact factor:   4.438


  5 in total

1.  Mosaicism in 45,X Turner syndrome: does survival in early pregnancy depend on the presence of two sex chromosomes?

Authors:  K R Held; S Kerber; E Kaminsky; S Singh; P Goetz; E Seemanova; H W Goedde
Journal:  Hum Genet       Date:  1992-01       Impact factor: 4.132

Review 2.  Gene-rich chromosome regions and autosomal trisomy. A case of chromosome 3 trisomy mosaicism.

Authors:  E M Kuhn; G E Sarto; B J Bates; E Therman
Journal:  Hum Genet       Date:  1987-11       Impact factor: 4.132

3.  An improved, non-isotopic method of screening cells from patients with abnormalities of sexual differentiation for Y chromosomal DNA content.

Authors:  M Witt; K Michalczak; A Latos-Bielenska; J Jaruzelska; I Kuczora; M Lopez
Journal:  J Med Genet       Date:  1993-04       Impact factor: 6.318

4.  Limitations of G-banding Karyotype Analysis with Peripheral Lymphocytes in Diagnosing Mixed Gonadal Dysgenesis.

Authors:  Ikuko Takahashi; Junko Miyamoto; Yukihiro Hasegawa
Journal:  Clin Pediatr Endocrinol       Date:  2006-08-02

5.  Startling mosaicism of the Y-chromosome and tandem duplication of the SRY and DAZ genes in patients with Turner Syndrome.

Authors:  Sanjay Premi; Jyoti Srivastava; Ganesan Panneer; Sher Ali
Journal:  PLoS One       Date:  2008-11-24       Impact factor: 3.240
  5 in total

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