Literature DB >> 6705189

Increase of intraerythrocytic fructose-1,6-diphosphate after incubation of whole human blood with fructose-1,6-diphosphate.

G Lazzarino, L Cattani, R Costrini, L Mulieri, A Candiani, L Galzigna.   

Abstract

The incubation of whole blood with fructose-1,6-diphosphate (FDP) entails a statistically significant increase of intraerythrocytic FDP together with a decrease of blood glucose. The increase is not significant when equimolar amounts of fructose plus twice molar phosphate are used. The effect of FDP is decreased in the presence of an excess of oxygen. FDP added to the whole blood is removed from plasma by the activity of plasma enzymes and by the presence of blood cells as well. No specific interaction of FDP with plasma proteins seems to occur and the effects of FDP addition last longer than is compatible with the presence of FDP in the plasma.

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Year:  1984        PMID： 6705189     DOI： 10.1016/s0009-9120(84)90480-6

Source DB:  PubMed          Journal:  Clin Biochem        ISSN： 0009-9120            Impact factor:   3.281


  9 in total

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5.  Energy metabolism in hypoxic astrocytes: protective mechanism of fructose-1,6-bisphosphate.

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Journal:  Nat Commun       Date:  2021-07-16       Impact factor: 14.919
  9 in total

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