Literature DB >> 670410

Serum immunoglobulin concentrations before and after splenectomy in patients with homozygous beta-thalassaemia.

M Constantoulakis, D Trichopoulos, O Avgoustaki, J Economidou.   

Abstract

Serum IgM, IgA, and IgG concentrations were measured in 19 patients suffering from blood-dependent homozygous beta-thalassaemia. The study was prospective and the same patients served as presplenectomy controls. IgG levels rose rapidly and continuously after splenectomy IgA levels also rose but not so sharply. IgM fell to low levelr pattern was found in the cross-sectional part of the study comprising 39 splenectomised and 51 non-splenectomised patients who were tested once.

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Year:  1978        PMID: 670410      PMCID: PMC1145343          DOI: 10.1136/jcp.31.6.546

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN: 0021-9746            Impact factor:   3.411


  11 in total

1.  Postsplenectomy infection in Cooley's anemia. An appraisal of the problem in this and other blood disorders, with a consideration of prophylaxis.

Authors:  C H SMITH; M E ERLANDSON; G STERN; M W HILGARTNER
Journal:  N Engl J Med       Date:  1962-04-12       Impact factor: 91.245

2.  Frequency of antibodies to various antigenic determinants in polytransfused patients with homozygous thalassaemia in Greece.

Authors:  J Economidou; M Constantoulakis; O Augoustaki; M Adinolfi
Journal:  Vox Sang       Date:  1971-03       Impact factor: 2.144

3.  Serum-immunoglobulin levels in thalassaemia and the effects of splenectomy.

Authors:  C Wasi; P Wasi; P Thongcharoen
Journal:  Lancet       Date:  1971-07-31       Impact factor: 79.321

4.  Infection and iron overload in thalassemia.

Authors:  L Caroline; P J Kozinn; F Feldman; F H Stiefel; H Lichtman
Journal:  Ann N Y Acad Sci       Date:  1969-11-20       Impact factor: 5.691

5.  Infections after splenectomy.

Authors:  M Constantoulakis; P Economopoulos; A Constantopoulos
Journal:  Ann Intern Med       Date:  1973-05       Impact factor: 25.391

6.  Risk of severe infection in patients with Hodgkin's disease or lymphoma after diagnostic laparotomy and splenectomy.

Authors:  R K Desser; J E Ultmann
Journal:  Ann Intern Med       Date:  1972-07       Impact factor: 25.391

7.  The hazard of infection following splenectomy in children.

Authors:  W D Erickson; E O Burgert; H B Lynn
Journal:  Am J Dis Child       Date:  1968-07

8.  Serum immunoglobulins in beta-thalassaemia after splenectomy.

Authors:  B Seitanidis; A Mihas; B Angelopoulos
Journal:  Acta Haematol       Date:  1971       Impact factor: 2.195

9.  Hazard of overwhelming infection after splenectomy in childhood.

Authors:  A J Eraklis; S V Kevy; L K Diamond; R E Gross
Journal:  N Engl J Med       Date:  1967-06-01       Impact factor: 91.245

10.  Splenectomy in homozygous beta thalassaemia: a retrospective study of 30 patients.

Authors:  D Engelhard; G Cividalli; E A Rachmilewitz
Journal:  Br J Haematol       Date:  1975-11       Impact factor: 6.998

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  8 in total

1.  Intradermal hepatitis B vaccine in thalassaemia and sickle cell disease.

Authors:  Q Mok; G Underhill; B Wonke; M Aldouri; M Kelsey; D Jefferies
Journal:  Arch Dis Child       Date:  1989-04       Impact factor: 3.791

2.  Serum immunoglobulins, IgG subclasses, isohemagglutinins and complement-3 levels in patients with thalassemia major.

Authors:  C Vergin; N Kutukculer; N Cetingul; G Nisli; S Caglayan; S Oztop
Journal:  Indian J Pediatr       Date:  1997 Mar-Apr       Impact factor: 1.967

3.  Increased IgM levels associated with splenosis?

Authors:  B Harding; J O'Grady; C McCarthy; F Given; H McMahon; B Murphy
Journal:  Ir J Med Sci       Date:  1987-06       Impact factor: 1.568

4.  Immunological abnormalities in thalassaemia major. I. A transfusion-related increase in circulating cytoplasmic immunoglobulin-positive cells.

Authors:  A N Akbar; P J Giardina; M W Hilgartner; R W Grady
Journal:  Clin Exp Immunol       Date:  1985-11       Impact factor: 4.330

5.  Immune functions in splenectomized thalassaemic children.

Authors:  J Ahluwalia; U Datta; R K Marwaha; S Sehgal
Journal:  Indian J Pediatr       Date:  2000-12       Impact factor: 1.967

6.  Alloimmunization to Red Cells and the Association of Alloantibodies Formation with Splenectomy Among Transfusion-Dependent β-Thalassemia Major/HbE Patients.

Authors:  Suteenee Jansuwan; Orathai Tangvarasittichai; Surapon Tangvarasittichai
Journal:  Indian J Clin Biochem       Date:  2014-02-16

7.  [Alterations of humoral and cellular immunity after splenectomy (author's transl)].

Authors:  M Winkelmeyer; K Littmann; O Thraenhart; G Tichy; E K Kuwert; F W Eigler
Journal:  Klin Wochenschr       Date:  1981-05-15

8.  Differential inhibition of the MLR by iron: association with HLA phenotype.

Authors:  C F Bryan; K Nishiya; M S Pollack; B Dupont; M de Sousa
Journal:  Immunogenetics       Date:  1981       Impact factor: 2.846

  8 in total

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