Lymphoma of the frontal sinus. Case report and review of literature.

A 43-year-old woman had an unusual case of non-Hodgkin's lymphoma (NHL) of the frontal sinus. Although the tumor was not diagnosed until after gross intracranial extension had already occurred, the patient's condition responded excellently to surgical debulking, frontal sinus obliteration, and chemotherapy. To date, she has had no neurologic sequelae or evidence of recurrence. In the past, stage 1 and 2 NHL of the nasal cavity and paranasal sinuses has been treated with primary radiation therapy, but a review of the literature shows that treatment failure is common in these cases.