Literature DB >> 6703595

Transdermal scopolamine in the treatment of acute vertigo.

R W Babin, T J Balkany, W E Fee.   

Abstract

A double-blind, parallel investigation was undertaken to evaluate the efficacy of transdermally delivered scopolamine hydrobromide in acute vertigo as compared to meclizine hydrochloride and placebo. Statistical analysis of subjective patient responses and clinical observations suggested that both scopolamine and meclizine are more effective than placebo. Both have significant, but different, side effects.

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Year:  1984        PMID: 6703595     DOI: 10.1177/000348948409300106

Source DB:  PubMed          Journal:  Ann Otol Rhinol Laryngol        ISSN: 0003-4894            Impact factor:   1.547


  7 in total

1.  Prevention of peripheral side-effects of transdermal hyoscine by adjunctive therapy with low dosage of pyridostigmine.

Authors:  I Ziv; D Versano; M Ruach; S Izraeli; S Almog; A Alhalel; M Alkalay; S Menahem; Z Tochner
Journal:  Br J Clin Pharmacol       Date:  1992-05       Impact factor: 4.335

Review 2.  Transdermal scopolamine for prevention of motion sickness : clinical pharmacokinetics and therapeutic applications.

Authors:  Zohar Nachum; Avi Shupak; Carlos R Gordon
Journal:  Clin Pharmacokinet       Date:  2006       Impact factor: 6.447

Review 3.  Drugs affecting the inner ear. A review of their clinical efficacy, mechanisms of action, toxicity, and place in therapy.

Authors:  C H Norris
Journal:  Drugs       Date:  1988-12       Impact factor: 9.546

4.  The dizzy elderly patient.

Authors:  J Ruth; B Goldlist
Journal:  Can Fam Physician       Date:  1986-12       Impact factor: 3.275

5.  Effect of low doses of scopolamine on RR interval variability, baroreflex sensitivity, and exercise performance in patients with chronic heart failure.

Authors:  B Casadei; J Conway; C Forfar; P Sleight
Journal:  Heart       Date:  1996-03       Impact factor: 5.994

Review 6.  New potential uses for transdermal scopolamine (hyoscine).

Authors:  M T La Rovere; G M De Ferrari
Journal:  Drugs       Date:  1995-11       Impact factor: 9.546

Review 7.  Transdermal hyoscine (Scopolamine). A preliminary review of its pharmacodynamic properties and therapeutic efficacy.

Authors:  S P Clissold; R C Heel
Journal:  Drugs       Date:  1985-03       Impact factor: 9.546

  7 in total

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