| Literature DB >> 6701185 |
D R Abernethy, D J Greenblatt, R I Shader.
Abstract
A sensitive (to 5.0 ng/ml) and specific method for analysis of the antidepressant trazodone is described. The method utilizes gas-liquid chromatography with nitrogen-phosphorus detection. Applicability of the method is demonstrated by (1) a pharmacokinetic study in a normal volunteer who received 50 mg trazodone orally and (2) steady-state plasma level determinations of 2 patients receiving trazodone in the treatment of depression.Entities:
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Year: 1984 PMID： 6701185 DOI： 10.1159/000137941
Source DB: PubMed Journal: Pharmacology ISSN： 0031-7012 Impact factor: 2.547