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Literature DB >> 670085

Globomycin, a new peptide antibiotic with spheroplast-forming activity. III. Structural determination of globomycin.

M Nakajima, M Inukai, T Haneishi, A Terahara, M Arai, T Kinoshita, C Tamura.

Abstract

The structure of globomycin has been determined by mass, PMR and CMR spectra and by chemical degradation. Globomycin is a new cyclic peptide antibiotic composed of L-serine, L-allo-threonine, glycine, N-methylleucine, L-allo-isoleucine and 3-hydroxy-2-methylnonaic acid. Among these components, L-allo-threonine, L-allo-isoleucine and 3-hydroxy-2-methylnonaic acid are novel components from natural products. A newly developed mass analysis has been introduced for determining the diastereoisomers of allo-threonine.

Entities: Chemical

Mesh：

Substances：

Year: 1978 PMID： 670085 DOI： 10.7164/antibiotics.31.426

Source DB: PubMed Journal: J Antibiot (Tokyo) ISSN： 0021-8820 Impact factor: 2.649

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Cited

10 in total

1. Existence of the bound form of prolipoprotein in Escherichia coli B cells treated with globomycin.

Authors: M Inukai; M Takeuchi; K Shimizu; M Arai
Journal: J Bacteriol Date: 1979-12 Impact factor: 3.490

2. The 34-kilodalton membrane immunogen of Treponema pallidum is a lipoprotein.

Authors: M A Swancutt; J D Radolf; M V Norgard
Journal: Infect Immun Date: 1990-02 Impact factor: 3.441

3. Characterization of CmaA, an adenylation-thiolation didomain enzyme involved in the biosynthesis of coronatine.

Authors: Robin Couch; Sarah E O'Connor; Heather Seidle; Christopher T Walsh; Ronald Parry
Journal: J Bacteriol Date: 2004-01 Impact factor: 3.490

4. Globomycin sensitivity of Escherichia coli and Salmonella typhimurium: effects of mutations affecting structures of murein lipoprotein.

Authors: J S Lai; W M Philbrick; S Hayashi; M Inukai; M Arai; Y Hirota; H C Wu
Journal: J Bacteriol Date: 1981-01 Impact factor: 3.490

5. Preferential selection of deletion mutations of the outer membrane lipoprotein gene of Escherichia coli by globomycin.

Authors: L J Zwiebel; M Inukai; K Nakamura; M Inouye
Journal: J Bacteriol Date: 1981-01 Impact factor: 3.490

Globomycin, a new peptide antibiotic with spheroplast-forming activity. III. Structural determination of globomycin.

1. Existence of the bound form of prolipoprotein in Escherichia coli B cells treated with globomycin.

2. The 34-kilodalton membrane immunogen of Treponema pallidum is a lipoprotein.

3. Characterization of CmaA, an adenylation-thiolation didomain enzyme involved in the biosynthesis of coronatine.

4. Globomycin sensitivity of Escherichia coli and Salmonella typhimurium: effects of mutations affecting structures of murein lipoprotein.

5. Preferential selection of deletion mutations of the outer membrane lipoprotein gene of Escherichia coli by globomycin.

6. Lipoprotein biosynthesis as a target for anti-Wolbachia treatment of filarial nematodes.

7. Effect of Novel Compound LX519290, a Derivative of l-allo Threonine, on Antioxidant Potential in Vitro and in Vivo.

Review 8. Bacterial Signal Peptides- Navigating the Journey of Proteins.

9. Analysis of lipoprotein transport depletion in Vibrio cholerae using CRISPRi.

Review 10. Mode of action of lipoprotein modification enzymes-Novel antibacterial targets.